Bioinformatics Explained @XBioinformat
Love to bring molecules to life by animating them. I will be posting pretty much only about that. #SciArt #MedArt #SciCom Oslo, Norway Joined January 2021-
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How does one search for relevant mentions of the following human genes in the scientific literature? - IMPACT (uniprot.org/uniprot/Q9P2X3) - PIGS (uniprot.org/uniprot/Q96S52) - NHS (uniprot.org/uniprot/Q6T4R5) - SHE (uniprot.org/uniprot/Q5VZ18) @uniprot
@buildmodels Amazing, I made a 360º render of #7DF3, #SARS_CoV_2 S trimer, S-closed (on the left) and #7DK3 #SARS_CoV_2 trimer, S-open (on the right).
Animation around #SARSCoV2 #Spike mutations and deletions inferred to occur in the "UK variant" (B.1.1.7, 20I/501Y.V1) based on a report from @arambaut @pathogenomenick @EvolveDotZoo @wendybarclay11 @erikmvolz et al. for @CovidGenomicsUK
From 2020.02.05 to 2021.01.27 at least 227 structures of #SARSCoV2 Main Protease were released on @buildmodels/@PDBeurope. More than half of them are authored by @FrankvonDelft, @Darenfearon, @DiamondLightSou, @MartinWalshDLS, @thesgconline, @london_lab, @rachaelskyner.
All available #SARSCoV2 #Nsp3 structures from @buildmodels/@PDBeurope combined. The bulk being resolved by @fraser_lab, @mctucsf & @Darenfearon, @IvanAhelLab, @FrankvonDelft. Only chains A shown. Structures with high RMSD to ref excluded. #COVID19
Cryo-EM structure of mature #Dengue #virus serotype 2. Reported by @CarriqueLoic, @Itziar_Serna, @denishkaria, @SerbanIlca, @jonathan_grimes, et al.
#SARSCoV2 Spike protein, visualization of the #N501Y mutation at the protein-protein interface with #ACE2. Crystal structure deposited on @buildmodels by Jason Gorman, @strangeatoms et al. from @Columbia.
Impressive work by @Darenfearon, @IvanAhelLab, @FrankvonDelft et al. Data from PanDDA analysis of #SARS_CoV_2 #Nsp3. This render is a combination of 104 PDBs from @rcsbPDB @buildmodels @PDBeurope. Only one protein structure shown, used to align the ligands from all the others.
SARS-CoV-2 spike protein notable mutations. Based on the structure 7KNI from @rcsbPDB deposited by researchers from @Columbia @NIH @JohnsHopkins #n501y #D614G #E484K #SARSCoV2 #SARS_CoV_2 #Covid_19

Brady Johnston @bradyajohnston
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rcsb pdb 💉🧬💻... @buildmodels
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