David Li @_David_Li
BioE PhD Student @Stanford with Hie/Fischbach/Deisseroth labs, previously Scheres group @MRC_LMB, Zhang lab @broadinstitute, @MIT '22 Joined April 2018-
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Carina is brilliant, excited to see where this leads!
Carina is brilliant, excited to see where this leads!
Excited to announce mBER, our fully open AI tool for de novo design of epitope-specific antibodies. To validate, we ran the largest de novo antibody experiment to date: >1M designs tested against 145 targets, measuring >100M interactions. We found specific binders for nearly half…
💥 We're hiring our first research scientists for OpenAI for Science! As a reminder, our goal is to build the next great scientific instrument: an AI-powered platform that accelerates scientific discovery.
New in-depth blog post time: "Inside NVIDIA GPUs: Anatomy of high performance matmul kernels". If you want to deeply understand how one writes state of the art matmul kernels in CUDA read along. (Remember matmul is the single most important operation that transformers execute…
(1/8) We’re releasing an 8-GPU Llama-70B inference engine megakernel! Our megakernel supports arbitrary batch sizes, mixed prefill+decode, a paged KV cache, instruction pipelining, dynamic scheduling, interleaved communication, and more! On ShareGPT it’s 22% faster than SGLang.
Excited to share this work from my PhD! See our structure below of a computationally designed IL-21 mimic with anti-tumor efficacy in mice. A collaboration between the David Baker, Stephanie & Mike Dougan, Warren Leonard, and Chris Garcia labs.
Excited to share this work from my PhD! See our structure below of a computationally designed IL-21 mimic with anti-tumor efficacy in mice. A collaboration between the David Baker, Stephanie & Mike Dougan, Warren Leonard, and Chris Garcia labs.
Super excited to share what we’ve been working on in collaboration with @SynBioGaoLab over the past few months on de novo antibody design. Check out this great thread by our team lead @santimillef highlighting the technical aspects of the pipeline!
Super excited to share what we’ve been working on in collaboration with @SynBioGaoLab over the past few months on de novo antibody design. Check out this great thread by our team lead @santimillef highlighting the technical aspects of the pipeline! https://t.co/MZ5eQAIPwZ
🚨 The 2026 Hertz Fellowship application is now open! 🚨 Hertz Fellows receive more than five years of funding—they gain the Freedom to Innovate® and the support of a lifelong community dedicated to their success. From symposia and mentorship to professional development and…
Thrilled to share that today we report our human protein interactome in @ScienceMagazine! Predicting which pairs of proteins in the human proteome is a great challenge due to the shallow eukaryotic evolutionary signals but hugely important to understand. science.org/doi/10.1126/sc…
Some very clever engineering by @ntperry13 and team!
Some very clever engineering by @ntperry13 and team!
Calling Bay Area math enthusiasts interested in weekly sessions doing rigorous foundational mathematics the modern way - with computer-verified proofs in Lean. (An experiment in rigorous math education outside traditional academia) course info - docs.google.com/document/d/1bC……
We sought to make proteins both potent and FAST. We used #proteindesign to design precise control over protein interaction lifetimes, enabling us to construct rapid-response circuits, biosensors, and switchable cytokines. Now published @Nature! Links to paper and tutorial below.
Entering my PhD, de novo antibody design was a grand challenge I thought would not be solved without huge increases in affinity data and Ab-Ag structure. Only 2 years later, we provide the first open-source recipe to get antibody binders, almost magically, out of a computer (1/3)
Entering my PhD, de novo antibody design was a grand challenge I thought would not be solved without huge increases in affinity data and Ab-Ag structure. Only 2 years later, we provide the first open-source recipe to get antibody binders, almost magically, out of a computer (1/3)
Today, we report Germinal, a method for efficient de novo antibody design, with @santimillef and @SynBioGaoLab. Germinal achieves success rates of 4-22% across diverse epitopes. We make the work fully open, without doing lame things like posting a preprint without methods. 🧵
This work would not have been possible without every single member of our amazing team: @_jnwang & @talaldotpdb for building the pipeline, @driscoll_cl @haoyu_dai_dhy @Xiaowei0402 for designing + rocking the wet lab experiments, and @SynBioGaoLab & @BrianHie for support +…
The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science. Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving 4–22% success rates with efficient experimental…
What’s the deal with all these science competitions? Me for @TheScientistLLC big thanks to @genophoria @yusufroohani @abhinadduri @MartinBJensen for speaking with me! the-scientist.com/how-science-co…
We are excited to share GPN-Star, a cost-effective, biologically grounded genomic language modeling framework that achieves state-of-the-art performance across a wide range of variant effect prediction tasks relevant to human genetics. biorxiv.org/content/10.110… (1/n)
Very excited to share our paper "De novo Design of All-atom Biomolecular Interactions with RFdiffusion3", now on BioRXiv. biorxiv.org/content/10.110… 1/n
We previously built programmable RNA sensors based on editing by housekeeping ADAR enzymes. But they can't sense arbitrary sequences due to design constraints (analogous to PAM for CRISPR). With our new "modulADAR", we overcome that constraint by leveraging ADAR's modularity.
Sergey Ovchinnikov @sokrypton
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Julia Joung @JuliaJoung
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Kelly Nguyen @KellyTHD_Nguyen
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Yang Yang @yyang_cella
764 Followers 484 Following Assistant Professor@VAInstitute, alimni of @MRC_LMB. cryo-EM, X-ray crystallography, Neurodegenerative disorder, GPCRs, virology.
Max Wilkinson @maxewilkinson
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Joseph Choy @josephtychoy
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R Wang @_rzwang
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CHRIS DOLINSKI | APIN... @1dolinski
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Nayim GR @Nayimcete
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Vocsolo @Vocsolo
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James Briggs @JamesABriggs
97 Followers 232 Following Schmidt Science Fellow @Harvard @SchmidtFellows
Alejo Rodriguez-Frati... @AlejoFraticelli
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Marçal Comajoan Cara @marcal_cc
41 Followers 498 Following phd student @berkeley_ai & research affiliate @stanford! research in ai for autonomous scientific discovery and to advance genetics
Jessica Sacher, PhD @JessicaSacher
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108 Followers 2K Following building large neural nets for biology @stanford • investing @ldvpartners • @quadfellowship • prev @2seventybio (acq by @regeneron) • @umich
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Artur Szałata @arturszalata
750 Followers 4K Following Machine learning for molecular biology. @ELLISforEurope PhD student @fabian_theis lab. @EPFL_en alumnus.
Ofir Press @OfirPress
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Varun Tekur @vtech74
159 Followers 974 Following PhD Student @ColumbiaSysBio | prev @nablabio, @SnorkelAI, @Harvard CS
Evan DeTurk @evandeturk
92 Followers 205 Following Incoming @Cambridge_Uni history of science | via Doudna Lab, @Princeton Bassler Lab | Demystifying biotech + biosecurity https://t.co/BbwIaDYyiH 🧬🧪☣️
Thurin Lemonshoe @ThurinLemonshoe
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Qiyu @yupines
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Matthew Clarke @Matthew05049818
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Itay Rosenbach @itay_ros
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Arvind Muruganantham @arvindmuru
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Daniel Uribe, MBA �... @duribeb
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Eric J. South @ericsouth_
137 Followers 307 Following PhD Candidate in the @DunlopLab/@BioDesignCenter at Boston University. Systems, synthetic, and computational biology. Prev @ImperialCollege @JMU
Hannah Barsouk @HBarsouk
65 Followers 152 Following Grad student @StanfordBiochem and @Stanford_ChEMH | @yaleMBB ‘25 ! | 🇺🇦🏳️🌈
Trevor Campbell @TrevorCampbell_
1K Followers 6K Following Problem Slayer 👾⚔️ Cooking up many new things in Biotech 🫁… Tinkerer and multi-modal human. Ex-ChemEng + Healthcare + Pharma. World’s 5th friendliest guy 🏅
Bebeto @Bebetou60702079
3 Followers 490 Following
Rui Yip @rui_yip
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Siddharth Betala @SiddharthBetal
234 Followers 4K Following ML @entalpic_ai || 24 || IIT Madras || Prev interns @ UofT, UW || Interested in NLP, Evals and AI4Science
David R. Liu @davidrliu
74K Followers 64 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Sergey Ovchinnikov @sokrypton
16K Followers 4K Following Scientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologist, 🇺🇦 No Human is illegal. Moving to: https://t.co/sow6IRD3jj
Julia Joung @JuliaJoung
2K Followers 418 Following Postdoc in the lab of Jonathan Weissman @WhiteheadInst. PhD Feng Zhang lab | @MITdeptofBE | @broadinstitute
Joseph Watson @_JosephWatson
3K Followers 97 Following Co-Founder @ Xaira Therapeutics Former Baker Lab PostDoc at @UWproteindesign. Interested in generative modelling for molecular design. Views my own.
Daan C. Swarts @DCSwarts
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Feng Zhang @zhangf
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Sjors Scheres @SjorsScheres
15K Followers 1 Following This account is no longer in use. Follow our science on: https://t.co/mlxULCj9zl
Arjun Raj @arjunrajlab
28K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12
Elliot Hershberg @ElliotHershberg
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Mo Khalil @MoKhalilLab
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Harmit S. Malik @HarmitMalik
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Nature Biotechnology @NatureBiotech
319K Followers 2K Following Publishing the best of biotech science and business. Find us on Bluesky, Facebook & Instagram. Part of @SpringerNature and @NaturePortfolio.
Kevin K. Yang 楊凱�... @KevinKaichuang
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Liz Kellogg ❄️�... @kellogg_liz
4K Followers 993 Following Assoc. Member @St Jude Structural Biology, Pew Biomed. Scholar 2021, Margaret Dayhoff Oakley Awardee 2023, Co-host of #ThePlungePodcast w/@mcianfro & @mimi1inh
Itai Yanai @ItaiYanai
32K Followers 2K Following Professor at the NYU School of Medicine. Co-host of the 'Night Science Podcast' @nightsciencepod and Co-founder of the Night Science Institute https://t.co/lede3rBmXU
Patrick Cramer @mpgpresident
14K Followers 577 Following President of the Max Planck Society since 2023 – dedicated to advancing science for the benefit of society. | @maxplanckpress
Lacra Bintu @BintuLacra
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Typas Lab @TypasLab
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LaurieWired @lauriewired
106K Followers 285 Following researcher @google; serial complexity unpacker; https://t.co/Vl1seeNgYK ex @ msft & aerospace
Simon Guo @simonguozirui
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Rohan Pandey @khoomeik
40K Followers 2K Following descending cross-entropy to ascend entropy @PeriodicLabs || prev research @OpenAI @CarnegieMellon '23
Michael Zhang @mzhangio
2K Followers 549 Following founding tech staff member @periodiclabs cs phd @hazyresearch, @StanfordAILab LLM reasoning, robustness, (r)efficiency, rl
Juan C Osorio MD @juanosoriomd
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Stuart Sul @stuart_sul
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Jordan Juravsky @jordanjuravsky
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Peggy Wang @peggy_wang
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432 Followers 232 Following Accelerating TB Research - Training the Next Generation of TB Scientists - Innovative Discoveries - Translation of Evidence to Policy, Practice, Diplomacy.
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Michael Koeris @mkoeris
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Simran Arora @simran_s_arora
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Jasper Butcher @butcher_jasper
171 Followers 47 Following BakerLab PhD Student in CS @ UW | MChem Oxford | Enzyme Design
Tom Watkins @tbkwatkins
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Robert Nelsen @rtnarch
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Luma AI @LumaLabsAI
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Jude Wells @_judewells
998 Followers 2K Following PhD student University College London: machine learning methods for structure-based drug discovery.
Akira Nishii @akiranishii3
108 Followers 2K Following building large neural nets for biology @stanford • investing @ldvpartners • @quadfellowship • prev @2seventybio (acq by @regeneron) • @umich
Ashwin Gopinath @ashwingop
859 Followers 760 Following Prof. @MIT (on leave) ; Building AI Scientist https://t.co/LhjmEzU1Aa; Random musings at https://t.co/C2NpmjSraH.
Biostate AI @biostateai
826 Followers 43 Following Biostate AI's mission is to develop generative AI that can benefit all of human health.
Claudia Driscoll @driscoll_cl
162 Followers 396 Following postdoc w/ Brian Hie @Stanford and @arcinstitute | prev DPhil @BiochemOxford @UnivCamPharm
Scott Gray @scottgray76
9K Followers 794 Following GPU Geek at @OpenAI. I have a long standing interest in neuroscience and its application to machine learning. He/Him.
John Carmack @ID_AA_Carmack
1.1M Followers 275 Following AGI at Keen Technologies, former CTO Oculus VR, Founder Id Software and Armadillo Aerospace
Jing Yu Koh @kohjingyu
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Standard Kernel Co. @Standard_Kernel
839 Followers 1 Following Building AI Infrastructure with AI; fast kernels go brrr
Amir Momen Roknabadi @ARoknabadi
99 Followers 141 Following Director of AI at @Thernabio, working on programmable RNA design. Built RNA models at @Exaibio. Previously at @Princeton & @Columbia.
Esther Lin @estheroate
1K Followers 488 Following CS PhD @UofT | Computational Imaging, Optics + ML | Prev: @realitylabs, @Adobe, @Tesla
Altera @Altera_AL
5K Followers 122 Following Building digital human beings that live, love, and grow with us. Starting in gaming.
Kevin Weil 🇺🇸 @kevinweil
111K Followers 3K Following CPO @OpenAI, BoD @Cisco @nature_org, LTC @USArmyReserve Prev: President @Planet, Head of Product @Instagram @Twitter ❤️ @elizabeth ultramarathons kids cats math
Duane Wesemann @duane_wesemann
194 Followers 37 Following
Rachel (Menghua) Wu @menghua_wu
506 Followers 142 Following MIT PhD '25 BS '19. LLM reasoning, ML for biology
Jingchuan Luo @JingchuanLuo
260 Followers 231 Following Damon Runyon fellow @Whitehead_Institute @Weissman_lab. @BCMB_JHMI alumni @JefBoeke Lab. studying localized translation in mammalian cells
Joshua Batson @thebasepoint
4K Followers 675 Following trying to understand evolved systems (🖥 and 🧬) interpretability research @anthropicai formerly @czbiohub, @mit math
Eric V Dang @EricVDang1
310 Followers 187 Following Immunologist and microbiologist | Incoming faculty at the Ragon Institute/Asst Prof of Immunology at HMS | Postdoc UCSF | UCSF PhD | Johns Hopkins '10 |
Yunsheng Tian @ CoRL2... @YunshengTian
969 Followers 736 Following 🤖 Applied Scientist @Amazon FAR (Frontier AI & Robotics) | PhD @MIT_CSAIL
Ticha Sethapakdi @tichaesque
464 Followers 289 Following PhD candidate @MIT_CSAIL · Previously @SCSatCMU and @CMU_CFA · Researching tools for extending creative expression 🎨🌈✨
Rocky Duan @rocky_duan
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Iain Dunning @iaindunning
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Stefano Massaroli @Massastrello
875 Followers 169 Following Researcher @ RIKEN | Co-founder @RadicalNumerics | AI ∩ numerics ∩ signal processing
Armin W. Thomas @athmsx
893 Followers 967 Following Co-Founder @RadicalNumerics | Prev: @LiquidAI_ and Data Science Fellow @StanfordData working with @HazyResearch and @russpoldrack | He/himTrends for United States
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