Nicholas Cheang @_immunogeNIC
👨🏻🔬@SAlonsoGroup PhD Student & Hardcore Immunologist l 🔍DC-targeting & sarbecovirus vaccines | Immune cell bias: B cells 👑 (Ironically, not DCs). linkedin.com/in/nicholas-ch… NUS, Singapore Joined January 2022-
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#Immunology out now @ScienceMagazine After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/lCPsea3 By Jobinet al.
3 days of hardcore B cells. Learnt alot from new research findings and the insightful scientific discussions during oral and poster sessions. Great experience and looking forward to more B cell science in future. 🤗 Thanks @KeystoneSymp for the amazing organizartion. #KSBcells25
Happy to share our latest work by @YYexin et al. on antibody-mediated control of endogenous retroviruses in mice. In the process, we found “natural antibodies” with broad reactivity against enveloped viruses. Here is how “panviral” antibodies work 🧵(1/) science.org/doi/10.1126/sc…
Very interesting read elucidating why the mRNA (and potentially other platforms) COVID-19 vaxx faces waning nAb. Which begs the qn, how do we design vaxx that promote LLPC generation and seeding?
Very interesting read elucidating why the mRNA (and potentially other platforms) COVID-19 vaxx faces waning nAb. Which begs the qn, how do we design vaxx that promote LLPC generation and seeding?
Check out our latest preview article in Cell @CellCellPress led by @MJMitchell_Lab PhD students @rohan_palanki + @hannahyamagata on @kedzierskalab's work identifying OLAH as a key enzyme that drives COVID-19 and other respiratory viral infections! Paper: cell.com/cell/fulltext/…
REVIEW @ImmunityCP Antibody modulation of B cell responses—Incorporating positive and negative feedback cell.com/immunity/fullt…
Loving the versatility of LNP technology. Hmmm, tying to my own work, how about conjugating the Clec9A mAb onto the LNP to deliver antigenic mRNA into cDC1? 🤔
Loving the versatility of LNP technology. Hmmm, tying to my own work, how about conjugating the Clec9A mAb onto the LNP to deliver antigenic mRNA into cDC1? 🤔
nature.com/articles/s4142… Happy to share our paper on Tfh specialization in antibody production on type-1 (virus) and type-2 immune responses (parasites, allergy). 1/11 #Tfhcells #germinalcentre #antibodies #immunology #bioinformatics. @kumar @IMM @FMUL @FilipaR @lgraca
1/ Increasing vaccine protection against #COVID. A/Prof @SAlonsoGroup @NUSingapore & A/Prof @LahoudMirei @MonashBDI have discovered a technique for prolonging immune response to #SARSCoV2 virus in pre-clinical models using an antibody construct. More: bit.ly/3yKN3Ek
1/ Increasing vaccine protection against #COVID. A/Prof @SAlonsoGroup @NUSingapore & A/Prof @LahoudMirei @MonashBDI have discovered a technique for prolonging immune response to #SARSCoV2 virus in pre-clinical models using an antibody construct. More: bit.ly/3yKN3Ek https://t.co/e3cnsTgHQq
Our new study just published in @CellRepMed shows that SARS-CoV-2 vaccine breakthrough infections (BTIs) have a positive effect on T cell responses! 1/8 cell.com/cell-reports-m… @SetteLab @Alba_Grifoni @profshanecrotty @P1RAD @TertuAPN @ljiresearch
Delighted to celebrate our latest publication with A/Prof Sylvie Alonso @SAlonsoGroup on dendritic cell-targeting of SARS-CoV-2 antigens for durable and protective immunity. A fantastic collaboration between @MonashBDI and @NUSingapore. doi.org/10.1016/j.ymth…

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Future Virology 2025 @2024_virology
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Pieta Mattila @mattilalab
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Marta Tarquis-Medina @MartaTarquis
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Kaiwen Chen @_kaiwenchen
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Mabtech @Mabtech
993 Followers 434 Following We are a Swedish company developing immunoassays for life science research.
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119 Followers 89 Following Viral host-pathogen interactions and developing subunit vaccines and antivirals are what we love. Led by @NUSMedAlonsoS. Tweets by lab members!
Hongyi @Hongyi_Michael
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Jonathan Markham @Jonathan428692
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geraldine🦠 @tinyroundblobs
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Mike Mitchell @MJMitchell_Lab
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15K Followers 934 Following A catalyst for accelerating life science discovery and connecting scientists within and across disciplines at symposia worldwide. RT does not imply endorsement.
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Prof. Akiko Iwasaki @VirusesImmunity
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Trends in Immunology @TrendsImmuno
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Nature Medicine @NatureMedicine
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Cell @CellCellPress
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Journal of Experiment... @JExpMed
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