Chryssa Zografou @_tickingclock
Greece Joined August 2017-
Tweets99
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Slide-tags unifies the single cell + spatial genomics worlds. It solves three key problems with existing spatial methods: 1) Cell segmentation (the biggest problem) 2) robustness and scalability (well-powered case-control studies now possible) 3) Multiomics (ATAC, RNA, etc)
Slide-tags unifies the single cell + spatial genomics worlds. It solves three key problems with existing spatial methods: 1) Cell segmentation (the biggest problem) 2) robustness and scalability (well-powered case-control studies now possible) 3) Multiomics (ATAC, RNA, etc)
New #PillarTalk available: Long-Live the Plasma Cell: The Basis of Sustained Humoral Immunity. ow.ly/B18c50Q8pRp #PlasmaCell #Antibodies #Bcells #J_immunol
What a fantastic paper - this will be in every Immunology class I give for a long time.
What a fantastic paper - this will be in every Immunology class I give for a long time. https://t.co/nodeszbJre
We're hiring! We are looking for a scientist to join our lab in Vari, Greece, and work on a new and exciting project! Check out below: maby.io/careers
The Chapter I of my postdoc journey at @KuchrooLab is now online! Beyond our findings, it's been an incredible human experience. We describe a B-cell state expressing checkpoint molecules uncovering Tim-1, as a potent regulator of anti-tumor immunity: nature.com/articles/s4158…. 1/5
Very interesting paper by @changhaohe42 et al out in @SciImmunology. They explore the effects of CD19 CARs with different affinities to lessen trogocytosis and find some cool effects on killing (see below). Link to article: science.org/doi/10.1126/sc… #CART #immunotherapy
Imagine you could stain whole adult mice with standard IgG antibodies. What you couldn't do! We present wildDISCO technology for this🤗, creating the first whole body vascular, lymphatic, and nerve atlases. By @HongchengM @jieluo692 biorxiv.org/content/10.110… 🧵👇🏼(turn on the sound)
A total of 13 FDA/EMA approved therapeutic antibodies in 2022, on par with 2021, and 2023 looks exciting! We put together this infographic and want to thank @TheAbSociety for compiling the data! (find Antibodies to watch in 2023 here hubs.la/Q01x-0xB0) #antibody
Jaechul Lim, Erica V. Lin, @Jun_Young_Hong, @RMedzhitov and colleagues @YaleIBIO suggest that #glucocorticoids, classically considered to be broadly immunosuppressive, have a selective immunostimulatory role in B cells. bit.ly/3BbJDIq #allergies
🔥 If you are interested in antibodies, vaccine design or B cells, you must read this new study about the effect of preexisting antibodies on vaccination. 👇👇👇 Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination medrxiv.org/content/10.110…
Fast track to personalized TCR T cell therapies dlvr.it/SQKFpK
“We found T cell clones shared between organs and characterized organ-dependent hypermutation rates among B cells.”
1/18 I am thrilled to share our collaborative project with Irit Sagi lab @LabSagi, led by Roei Mazor @Roei95188554, about anti-tumor antibodies in high-grade serous ovarian cancer (HGSOC) patients. cell.com/cell/fulltext/… @CellCellPres
Progress and challenges in mass spectrometry-based analysis of antibody repertoires cell.com/trends/biotech…
Tertiary lymphoid structures (TLS) generate and propagate anti-tumor antibody-producing plasma cells. Our story out in @ImmunityCP !! authors.elsevier.com/c/1efr~3qNrUqF…
Our newest study reveals some surprising immunology, which is relevant for vaccines. We immunized animals with a protein vax and waited to see how long germinal centers (GC) would last. Expectations were GCs would peak by 3 weeks & be gone by 6. How long did they actually last?🧵
Such an inspiring story
We just released CompAIRR – a tool that reduces greatly the longstanding computational bottleneck of identifying shared identical and similar sequences among large sets of immune repertoires. All the details/links are in the thread below. Feedback is very welcome! @airr_community
We just released CompAIRR – a tool that reduces greatly the longstanding computational bottleneck of identifying shared identical and similar sequences among large sets of immune repertoires. All the details/links are in the thread below. Feedback is very welcome! @airr_community

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EU Science & Innovati... @EUScienceInnov
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