Bastien Nguyen @bastien_nguyen

https://t.co/wwQJhW9g9C New York, NY Joined February 2009

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FabriceAndre @FAndreMD

3 years ago

Tks anirban ! RNA seq and whole exome in 1000 and 500 pretreated metastatic cancers. Interesting to see the impact of prior therapies, especially platinum, on DNA + discovery of new alterations involved in resistance (PTEN transloc). A huge work from PRISM (maybe futur center🤞)

Anirban Maitra @Aiims1742

3 years ago

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MSK Library @MSKLibrary

3 years ago

Featured today by @MSKLibrary: Outcomes and Molecular Features of Brain Metastasis in...dx.doi.org/10.1001/jamane… @bastien_nguyen @ahhanisha @JoanneF_Chou @VStrongMD @Daniela_Molena @ILSONDavid @CowzerDarren @nikolausschultz @md_kathryn @Dr_N_Moss @YJanjigianMD @SteveMaronMD

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Walid Chatila @chatila_w

3 years ago

Our latest manuscript studying rectal cancer is out in @NatureMedicine. This is work led by @DrGarciaAguilar, @fsanchezvega and myself, in collaboration with amazing colleagues at @MSKCancerCenter. 1/n nature.com/articles/s4159…

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Goutam Chakraborty @Goutam_Chak

3 years ago

PIK3R1-mutation regulates Insulin-PI3K-glycolytic pathway in #prostatecancer. Our @CCR_AACR paper shows frequent oncogenic alteration of PIK3R1 in #mCRPC @DrPhilKantoff @subhiii_n @nikolausschultz @PCF_Science @MSKCancerCenter @MountsinaiUro aacrjournals.org/clincancerres/…

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Barbara Marte @BarbMarte

4 years ago

new out in Nature, wonderful paper exploring the events in the first next cell cycle after whole genome duplication: nature.com/articles/s4158…

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Jake June-Koo Lee @jakelee0711

4 years ago

What a striking finding on questionable driver -- KRAS Q61K mutation. It seems like this is functional only when this coexists with adjacent silent mutation in G60 that abolishes cryptic splice site. Shocking deep biology from TKI resistance research. nature.com/articles/s4158…

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Jeremy Goecks @jgoecks

4 years ago

Our new @NCIHTAN paper has been published! It presents a unique spatial atlas of linked multimodal datasets from serial biopsies of a metastatic breast cancer evolving across multiple courses of therapy. 1/6 cell.com/cell-reports-m…

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Debyani Chakravarty, PhD 🇺🇦 @CDebyaniPhD

4 years ago

@ASCO Provisional Clinical Opinion re Somatic Genomic Testing in pts w/ Metastatic or Adv Cancer is out! An honor to be on this boat captained by @MarkRobsonMD & Drs. Funda Meric-Bernstam w/ Dr. Amber Johnson. ascopubs.org/doi/full/10.12…

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Cancer Cell @Cancer_Cell

4 years ago

Online Now: Metastasis and organotropism: A look through the lens of large-scale clinical sequencing data dlvr.it/SJQ1K0

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Cancer Discovery @CD_AACR

4 years ago

Read this week's Cancer Discovery #ResearchWatch Genomic Alterations Distinguish Patterns of Metastatic Dissemination by @nikolausschultz, @fsanchezvega, @bastien_nguyen, @CJFongPhD, @sloan_kettering. bit.ly/3oG7Ela

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Memorial Sloan Kettering Cancer Center @MSKCancerCenter

4 years ago

🚨 Breaking - Data from 25,000 patients is helping scientists at MSK's Sloan Kettering Institute answer — can a tumor's genetic mutations help predict whether and where cancer will spread? @CellPressNews @nikolausschultz @fsanchezvega @bastien_nguyen bit.ly/3uvXWFI

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NatureRevClinOncol @NatRevClinOncol

4 years ago

In a phase II study of the KIT inhibitor imatinib plus the MEK inhibitor binimetinib as first-line therapy for advanced-stage GIST, the ORR was 69%, mPFS was 29.9 months and mOS was not reached; toxicity was manageable: ascopubs.org/doi/full/10.12… #stcsm #scmsm #medonc #caxtx

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Vivek Subbiah, MD @VivekSubbiah

4 years ago

KIT+ MEK inhibition in GIST ➡️Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor ⭐️The best ORR was 69.0% @WTapMD @JTrentMDPhD @JCO_ASCO ascopubs.org/doi/full/10.12…

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Chai Bandlamudi @chaiband

4 years ago

Proud to share our work out today in @NatureGenet. With @srinipr4, @MFBerger1 and @BarryTaylorLab. nature.com/articles/s4158… We try to understand the extent to which cancers arising in patients with inherited pathogenic variants are actually mediated by the germline defect, 1/n

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Phil Kantoff @DrPhilKantoff

4 years ago

Black men die from prostate cancer twice as often as White men. @BrandonMahal, @FranklinHuang, @KOSJ12, and others have shown that tumors from Black men can be genomically different. Insights from Stopsack et al study out today @CCR_AACR. @PCFnews doi.org/10.1158/1078-0… 1/n

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Debyani Chakravarty, PhD 🇺🇦 @CDebyaniPhD

4 years ago

@OncoKB's @US_FDA tab is @FDAOncology recognized! A 3y journey & we couldn't be prouder to state we are the 1st somatic tumor mutation database w/ this accolade. @OncoKB is the combined dedicated effort to sustain a knowledge base powered by @SloanKettering clinical expertise.