Gaurav Venkataraman @gaurav_ven
Technologist & sociology enthusiast. Cofounder of Trisk Bio, working on manufacturing infrastructure for biology, in London. Reach out: [email protected] triskbio.com Joined March 2017-
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Gaurav Venkataraman retweeted
@elidourado "Expensive to manufacture" is relative to the currently not-so-great state of the art, there are people working on cheaper AAV like triskbio.com
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Gaurav Venkataraman retweeted
.@tylercowen a few months ago
Stuart is a very impressive person along many dimensions!
Stuart is a very impressive person along many dimensions!
We’ve all felt it. @jamesgiammona
OG biomanufacturing
I’ve found LLMs to be a remarkably fast way to learn math bc they force the user to read output the way that you’re *supposed* to read math textbooks: fighting every claim, checking counterexamples, being highly distrustful.
Gaurav Venkataraman retweeted
Barbara McClintock proposed – over 40 years ago – that transposable element activity could be a response to stress, and I think that we are still only beginning to understand how right she was.
Gaurav Venkataraman retweeted
The greater the number of data points per measurement, the easier it is to make spurious associations. This is why high-dimensional measurements (of e.g. the microbiome, epigenome, genome) can be linked to virtually anything, to the point of being meaningless.
The greater the number of data points per measurement, the easier it is to make spurious associations. This is why high-dimensional measurements (of e.g. the microbiome, epigenome, genome) can be linked to virtually anything, to the point of being meaningless.
Gaurav Venkataraman retweeted
Congratulations to my explorer-adventurer wife on the culmination of years of work sampling and mapping the microbial ecology of the south Pacific! Her thread does a great job contextualizing how cool this is, especially her discovery of increased horizontal gene transfer of…
Congratulations to my explorer-adventurer wife on the culmination of years of work sampling and mapping the microbial ecology of the south Pacific! Her thread does a great job contextualizing how cool this is, especially her discovery of increased horizontal gene transfer of…
Very big news.
Why not, indeed.
Working in LLM interpretability today must feel like what working as a theoretical physicist felt like in its golden age. A constant stream of shocking and interesting experimental findings that need to be explained.
Got to go thru waste counseling before I can receive a bigger trash bin. Isn’t there someplace I can upload pics of my daughters? cdn-eastherts.onwebcurl.com/s3fs-public/20…
Gaurav Venkataraman retweeted
@GS05445168 Not really. These AIs are good for designing drugs that bind to a specific protein, and that’s about it. This so-called “target-binding” ability of a drug is only one of about 50 different things you need optimize when developing a drug.
Gaurav Venkataraman retweeted
@GS05445168 For example, manufacturing the drugs on a large scale in an approved factory is actually a major bottleneck and represents the largest preclinical cost of making a drug - not target binding. Protein folding AIs also cannot predict the ADME properties of a drug.
No matter how highly you think of Tyler, prob still underrating
No matter how highly you think of Tyler, prob still underrating
Another absolute banger from Ryan Flynn. cell.com/cell/abstract/…
Gaurav Venkataraman retweeted
We're in a new era. "Regeneron’s gene therapy, dubbed DB-OTO, is a cell-selective AAV gene therapy for children with hearing loss stemming from a mutation to the otoferlin gene. The company snapped up DB-OTO through its $109 million acquisition of Decibel Therapeutics in 2023."…
Not easy to manufacture biologics. Even ‘simple’ ones, even when there is a lot of money at stake. theguardian.com/society/2025/f…
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