george davey smith @mendel_random
Joined February 2012-
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Our research shows that brachial measurements substantially overestimate aortic systolic blood pressure in adolescents and might result in an overdiagnosis of hypertension during screening journals.lww.com/jhypertension/… @DrChloePark @MRCLHA @mendel_random @laurahowe_epi @CO90s
@drjohnm @mendel_random Worth the time! Recording is now up x.com/venkmurthy/sta…
@drjohnm @mendel_random Worth the time! Recording is now up x.com/venkmurthy/sta…
Lectureship in Machine Learning for Health, now open for applications! In the Bristol Medical School, closing date 14th May 2024 – bristol.ac.uk/jobs/find/deta… Job number – ACAD107492 Contact me for an informal chat if interested.
Recording of must watch lecture for anyone who performs or reads studies using Mendelian randomization linked below 👇
Hey @TimandraHarknes here’s the link for the Mendelian Randomisation talk at @UCLHealthPublic last night. Shame you couldn’t be there in person and benefit from the free drinks afterwards ucl.zoom.us/rec/share/FlkD…
Two 4 year PhD opportunities @mrc_ieu with the legendary Tom Gaunt, closing date 20th May findaphd.com/phds/project/d… findaphd.com/phds/project/i…
RCTs & MR agree that HDL cholesterol does not protect against CHD pubmed.ncbi.nlm.nih.gov/32244255/ Now non-linear MR simply recapitulates the non-causal observational association pubmed.ncbi.nlm.nih.gov/38364900/ Can MR be made useful again? Hear tomorrow 4.30pm details at forms.office.com/pages/response…
This is science. @DREAM_trainees @CIRTNetwork @_DiabetesAction trainees Please take note 👇👇👇
This is science. @DREAM_trainees @CIRTNetwork @_DiabetesAction trainees Please take note 👇👇👇
4/n I'll be talking in person and on-line about the hole Mendelian randomization is in, and what can be done to dig it out from this, to become useful again @UCLHealthPublic 25th April 4pm UK time, registration required at forms.office.com/pages/response…
THE most impactful proponent of Mendelian randomization methods has pumped the breaks, acknowledging his concerns that MR can generate spurious relationships & overstated causal conclusions, especially in nonlinear associations. TLDR: 🤌obesity still not protective for mortality
THE most impactful proponent of Mendelian randomization methods has pumped the breaks, acknowledging his concerns that MR can generate spurious relationships & overstated causal conclusions, especially in nonlinear associations. TLDR: 🤌obesity still not protective for mortality
Obvious that zero covid psychologists knew little infectious disease epidemiology.Seems they were limited wrt to psychology too. Great paper by @BareReality @princessjack @rwjdingwall @LucyGoBag @michael_riordan @SelfHarmRes onlinelibrary.wiley.com/doi/full/10.10… COI: I have a psychology degree
Our next bake sale is this Thursday in the Staff Room between 10 and 11:30, raising money to support specialist treatment for a local little boy.
Agree @rlmcelreath though instrumental variables was co-invented with his economist father youtube.com/watch?v=z0kI35… & though Sewall Wright developed path analysis & use of causal anchors, he never used genetic IVs. 25/4 at 4.30pm more on the crisis in MR forms.office.com/pages/response…
Agree @rlmcelreath though instrumental variables was co-invented with his economist father youtube.com/watch?v=z0kI35… & though Sewall Wright developed path analysis & use of causal anchors, he never used genetic IVs. 25/4 at 4.30pm more on the crisis in MR forms.office.com/pages/response…
Too many things are called “shocking”here, but this evidence of the deep reach of corporate power in persecuting a brave GP engaged in attempting to improve our public health future merits the term. Dr Sarah Benn deserves any public support she can get
Too many things are called “shocking”here, but this evidence of the deep reach of corporate power in persecuting a brave GP engaged in attempting to improve our public health future merits the term. Dr Sarah Benn deserves any public support she can get
🚨 Interested in causal inference? Come join us for the Mendelian Randomisation conference, 19-21 June, @mrc_ieu This years themes include MR methods, drug target MR, mental health, disease progression & more! Register, submit your abstract 👇 mendelianrandomization.org.uk
Maarten van Smeden @MaartenvSmeden
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@mendel_random @TimandraHarknes @UCLHealthPublic Sorry to miss it myself also. And drinks obvs..
@mendel_random @TimandraHarknes @UCLHealthPublic The auto-subtitles give Adam introducing you as "Shady Smith"!
Tour de force lecture on the pitfalls of Mendelian randomization studies from a pioneer and giant in the field. When @mendel_random posts the recording, it will be a must watch!
RCTs & MR agree that HDL cholesterol does not protect against CHD pubmed.ncbi.nlm.nih.gov/32244255/ Now non-linear MR simply recapitulates the non-causal observational association pubmed.ncbi.nlm.nih.gov/38364900/ Can MR be made useful again? Hear tomorrow 4.30pm details at forms.office.com/pages/response…
@mendel_random We also found MR supports RCT effect of blood pressure lowering on risk of type two diabetes thelancet.com/pdfs/journals/… though it didn’t make it into the main manuscript in the end …
@Drlipid Good time to remember @mendel_random academic.oup.com/ije/article/49…
Can imagine the discussions if humans had this type of hetreogametic sex determination. (a) we'd be convinced it was one of the reasons why we are special (b) there would genuinely be more complex combinations
@mendel_random @GrainOfScience @OACJournal @ArthritisRes @ACR_Journals @mendel_random @JonTobias1 and I are planning a letter to JBMR about a dodgy MR study they’ve just published. But I think there is a wider problem in the omics fields - MR is the tip of the iceberg as there are many more dodgy omics papers that aren’t MR. Eg DEG based papers
Economics nerds I don't normally quote a Professor at the Cato institute but this is a rather fun example of why economics is now so detached - possibly than it has ever been. I fear Alfred Marshall, who (unlike me 😱) could do the maths would have been appalled.
Beautifully placed “possibly” in Alan Grafen’s ‘Should we ask for more than consistency of Darwinism with Mendelism?’ in Studies C (2019)
@DalalSci my grandfather was a sophomore when Thomas Hunt Morgan took him into his lab (Fly Room @ Columbia) and as a sophomore he computed the worlds 1st genetic map! sturtevant.com/sturtevant/ahs…
Paper mills are a threat to academia and science. Fraudulent papers are diluting the truth and making it harder to make real progress. @CurlyGeneticist shining an important light on this darker side of academia. #OARSI2024
@Leao_pel @PracheeAC I'm increasingly of the opinion posting peer-reviews publicly is essential primarily to demonstrate the article has actually been (competently) reviewed...
Stuck in car trying to explain to my mum what the debate around gender is about. We didn’t get much beyond chromosomes. She keeps asking if she’s gender neutral. So looking forward to explaining phalloplasty
Lord Byron died exactly 200 years ago today, after falling ill in Greece while gathering an army to fight the Ottoman Empire. Raise your game, Simon Armitage. There is plenty to be said about his death, and you will not struggle to find that. I, however, want to talk about..
@mendel_random Well said, George. I saw this too. How can doctors’ professional body find misconduct in a doctor with the courage to make a statement to protect people’s health?
Two proud supervisors standing next to our students work. Sadly Asad couldn’t come to #OARSI to present it himself. Just after this picture was taken someone came up to us to discuss his work. “When are you going to publish this….I want to cite it”. #musictoourears
Great presentation from @stephmck1971 on auditory processing of children with #Cleft using our data. History of hearing difficulties predicts later auditory processing #CFSGBI2024
It was lovely to be recognised by @OACJournal as a reviewer of the year at #OARSI.
Congratulations and thank you to the 2024 Reviewers of the Year for OAC and OAC Open Journal for your valuable contributions 🎉🙏🏻