Rebecca Shafee @rebecca_shafee
Neurogenetics Researcher at @NIMHgov. Prev. genetics and neuroscience @Harvard/@broadinstitute. PhD on black holes @harvardphysics. Mom. 🇧🇩 rebeccashafee.com Joined January 2017-
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#OSSD24 program here: ossdweb.org/ossd-2024-prog… Packed wt great sessions, including one chaired by Allan Mackenzie-Graham & me on "Mapping Sex Differences in Brain Organization Across Species and Spatial Scales" from 🤩 team: Jason Lerch @YangLabUCLA @elisa_guma @rebecca_shafee
#OSSD24 program here: ossdweb.org/ossd-2024-prog… Packed wt great sessions, including one chaired by Allan Mackenzie-Graham & me on "Mapping Sex Differences in Brain Organization Across Species and Spatial Scales" from 🤩 team: Jason Lerch @YangLabUCLA @elisa_guma @rebecca_shafee
When I thought I was done with the GWAS stories of 2023 and I should wrap up, @StephenORahilly dropped yet another great paper from his team. How can I resist? It's storytelling time. In this hot-off-the-press Nature paper, @DrFejzo et al. uncover an absolutely fascinating…
When I thought I was done with the GWAS stories of 2023 and I should wrap up, @StephenORahilly dropped yet another great paper from his team. How can I resist? It's storytelling time. In this hot-off-the-press Nature paper, @DrFejzo et al. uncover an absolutely fascinating… https://t.co/qX4UZMJqJk
Still at #ACNP2023 and want to hear about our work on sex differences in the genetic basis of human brain anatomy? Stop by Poster 153: Wednesday 5-7 pm! We performed sex-stratified genetic analyses across 1100 brain MRI phenotypes in 30,000 sample in the UKBiobank.
Great talk by Dr. Samantha Meltzler-Brody on postpartum depression at today’s presidentla plenary #ACNP2023. So encouraging to see great research being done in the fields of maternal mental health.
Looking forward to my first time at #ACNP2023 ! I will be presenting our work on sex difference in the common genetic architecture of the human brain at the Wednesday poster session! Also, my six year old wrote this poem and asked if I could read it at the meeting: 🐱 🐀 🎩 🧀
Looking forward to my first time at #ACNP2023 ! I will be presenting our work on sex difference in the common genetic architecture of the human brain at the Wednesday poster session! Also, my six year old wrote this poem and asked if I could read it at the meeting: 🐱 🐀 🎩 🧀 https://t.co/wJcTTpBk8G
Excited to present our work on sex difference in the common genetic architecture of brain anatomy at tomorrow’s poster session at #ashg2023. Poster # pb1323, 2:15 pm -4:15 pm.
(1/10) Excited to share our new preprint examining cross-species sex differences in brain anatomy in humans and mice: “Comparative neuroimaging of sex differences in human and mouse brain anatomy” biorxiv.org/content/10.110…. Description in thread.
Excited to present our work: "Sex-stratified analyses of common genetic influences on neuroanatomical variation in the UK Biobank" at the poster session. #2018, July 25 & 26, 12:45-14:45. #OHBM2023 @bogglerapture
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54K Followers 0 FollowingSO EXCITED to have this new study out - led by the one and only @AlexDeCasien (👀🧵⬇️. We use >15k RNAseq samples from GTEX to prise open a hotly debated axis of sex-biased biology … the “tug of war” between strangely conserved homologous gene pairs on the X and Y chromosome …
New preprint alert!🚨 Do you often find yourself thinking “what’s up with those genes that have (non-recombining) copies on the X & Y chromosomes?!”🧬👀 Probably not…but @bogglecapture & I think about these “gametolog” gene pairs quite a bit!🤔 (1/11) biorxiv.org/cgi/content/sh…
New preprint alert!🚨 Do you often find yourself thinking “what’s up with those genes that have (non-recombining) copies on the X & Y chromosomes?!”🧬👀 Probably not…but @bogglecapture & I think about these “gametolog” gene pairs quite a bit!🤔 (1/11) biorxiv.org/cgi/content/sh…
What we see / What ExA-SPIM sees Discover how these stunning images were captured: alleninstitute.org/news/a-new-cus…
What’s going on in Noosa? @DrBreaky’s twilight tour of cemetery kangaroos, with @bttyeo @jsdamoiseaux @adeelrazi @DanielMargulies @constable_todd @HelenJuanZhou @mallarchkrvrty1 @bogglerapture 🧠 #NoosaBrain2024
Delighted to share Transcriptional Cartography in @eLife (doi.org/10.7554/eLife.……) Our goal was to make dense cortical gene expression maps from the Allen Human Brain Atlas. We took the sparse samples and interpolated them into >20k downloadable gene expression maps. 1/n
When I thought I was done with the GWAS stories of 2023 and I should wrap up, @StephenORahilly dropped yet another great paper from his team. How can I resist? It's storytelling time. In this hot-off-the-press Nature paper, @DrFejzo et al. uncover an absolutely fascinating…
Great to see this coming out today nature.com/articles/s4158… Thanks to all the collaborators who made this happen. If you are interested to read more please see this blog bit.ly/GDF-15_HG_Blog/
🧬🧠 Check out our latest preprint on the genetics of impulsivity! medrxiv.org/content/10.110… In this paper, we examined ‘lumping’ versus ‘splitting’ models of impulsivity and characterized the shared and unique biology across multiple levels. A few key findings below! 🧵
First off, thank you for reading this far. We promise this initiative is worthy of your attention. 💥Next month the @UofCalifornia is announcing the launch of the Ann S. Bowers Women’s Brain Health Initiative. brainhealth-ucnoyce.rsvpify.com💥 (🧵1/11)
Evolutionary mechanisms underlying X-chromosome dosage compensation in organisms have always fascinated me. In a new paper in @Nature, Kalita et al. report their discovery of a novel gene that turned out to be the master regulator of X-chromosome dosage compensation in anopheles…
"Our findings indicate that both dengue burden and dengue incidence will peak sometime this century in Southeast Asia, before declining to historical levels or below depending on the prevailing climatic and socioeconomic conditions." Colón-González et al. Nat Comm…
(1/10) Excited to share our new preprint examining cross-species sex differences in brain anatomy in humans and mice: “Comparative neuroimaging of sex differences in human and mouse brain anatomy” biorxiv.org/content/10.110…. Description in thread.
@rebecca_shafee You have a PhD in astrophysics but you’re now publishing on imaging genetics data? You are my new hero!
A message to pregnant women — please give the baby your surname. You carried a baby for 9 months, gave birth, and will be responsible for that child for the rest of your life. When you’re registering the baby ask yourself: why is the father’s surname more important than yours?
So … my 12 year old daughter just introduced me to City Pop (70s Japanese soul/funk/disco) and - to borrow her vernacular - it SLAPS! 🕺🏽
SAPNA dinner at #OHBM2023! @OHBM @mnrajah @restingstate @adeelrazi @Aman_Badhwar @Raamana_ @nab_koirala 🧠🇮🇳🇵🇰🇧🇩
This is today! Multiscale, multimodal mapping at 3pm in 210A #OHBM2023
If you're coming to #OHBM2023 and fancy some juicy multiscale action, come by & visit our Monday 24th 3-5:15pm symposium on "Multiscale mapping of the cortex in health and disease" - featuring some sizzling science from @AlkemadeAnneke @misicbata @sofievalk @KonradWagstyl 🧠🧬🥳
If you're interested in sex differences in brain anatomy across species (humans and mice) come check out my poster @ 12:15 - 14:15 / #962. #OHBM2023 @bogglerapture
If you're at #OHBM2023 and interested in the neurobiology of sex differences - please check out these posters from postdocs extraordinaires @elisa_guma @rebecca_shafee ...
Excited to announce that this work, looking at the effects of sex-chromosome trisomy on human and mouse brain anatomy, is now published @SfNtweets #JNeurosci. Check out the final product here: jneurosci.org/content/early/…
Sex chromosome dosage affects neuroanatomy, but how do effects compare across species? Our new preprint tackles this question by studying global and regional brain anatomy in humans and mice with the same sex chromosome trisomies (XXY and XYY): biorxiv.org/content/10.110…