Seth Stafford @seth_stafford
Mindsmith forging simple minds for practical tasks at https://t.co/HbBu33ynny. DL is condensed matter physics in theory, but metallurgy in practice. @sethts.bsky.social San Carlos, CA Joined June 2009-
Tweets3K
-
Followers740
-
Following1K
-
Likes10K
please retweet to help get his attention! Yo @elonmusk whatever happened to your idea of allowing alternative feed algorithms and having a marketplace for them? that was an excellent idea.
Great headline! It’s really difficult to anticipate the shape major changes will take over time.
Models. [still!] Behaving. Badly. simonandschuster.com/books/Models-B…
Models. [still!] Behaving. Badly. simonandschuster.com/books/Models-B…
I like how Sacks gets off on lying about Biden instructing the Justice Department to prosecute Trump because he knows it would be virtually impossible for a president to sue for defamation. That means Sacks can make up any lie he wants with impunity.
I like how Sacks gets off on lying about Biden instructing the Justice Department to prosecute Trump because he knows it would be virtually impossible for a president to sue for defamation. That means Sacks can make up any lie he wants with impunity.
Watching this reminded me how DL is like quantum mechanics. At 26:17 @3blue1brown says "the . premise that . the calcs have to look like matrix mults" ... Back in the 1920's, QM was this weird "matrix mechanics" that just mysteriously worked.
Watching this reminded me how DL is like quantum mechanics. At 26:17 @3blue1brown says "the . premise that . the calcs have to look like matrix mults" ... Back in the 1920's, QM was this weird "matrix mechanics" that just mysteriously worked.
Nice application of RAG -- before RAG was a thing -- and their "representation" theorem is a plausible model of the novel kind of generalization we get from LLMs. arxiv.org/abs/2402.03175
Nice application of RAG -- before RAG was a thing -- and their "representation" theorem is a plausible model of the novel kind of generalization we get from LLMs. arxiv.org/abs/2402.03175
The last great political realignment occurred in the 1850s b/c the Whig Party could not cope with the problem of slavery and was replaced by the forthrightly anti-slavery Republican Party. Will the GOP now fall apart b/c it cannot cope with Trumpism/Fascism?
Really searing indictment of all the enablers in the Republican establishment from Mark Herrmann. The "party of Lincoln" emerged from the wreckage of the Whig party. Maybe it's time for a "new Whig" party? abovethelaw.com/2024/03/im-not…
Really searing indictment of all the enablers in the Republican establishment from Mark Herrmann. The "party of Lincoln" emerged from the wreckage of the Whig party. Maybe it's time for a "new Whig" party? abovethelaw.com/2024/03/im-not…
Excellent episode featuring Stuart Kauffman. Wide-ranging discussion on evolution, autocatalytic sets, constraint closure, open-endedness of biological and cultural evolution, etc. Well worth a listen. Some thoughts below:
Excellent episode featuring Stuart Kauffman. Wide-ranging discussion on evolution, autocatalytic sets, constraint closure, open-endedness of biological and cultural evolution, etc. Well worth a listen. Some thoughts below:
There's a big tax deal being negotiated in the Senate, and if you are employed by/own a company that makes software or any kind of technology, you need to know about it. Since taxes are boring, this will be explained entirely in Monty Python gifs.
Just to quickly point out why some of us would be very happy to see Biden back in the White House, apart from keeping the dictator out, let's recount the record.
Would it be great if the New York Times spent half as much time talking about Donald Trump wanting to end democracy in America as they do Joe Biden‘s age?
Elon Musk said "there is no way in hell" that Putin can lose the war in Ukraine. He believes that if Putin backed down, he would be assassinated Even if it were true, which it is not - so what? We have to resist aggressors and it is actually good if they lose power in process 1/
One guy stole nuclear secrets, shared classified information with Russia in the Oval Office, said he believed Putin more than the U.S. intel community, led an insurrection & just invited Russia to attack NATO and the other one misstated the job title of Egypt's leader.
I'm still waiting on this one. Aren't any of the pundits calling for Biden to drop out prepared to say that Donald Trump has a better grasp of reality?
I want to get the political reporters on record. Do any of the reporters insisting Biden step down think he has less grasp of reality than Donald Trump? Please retweet.
More Angry Biden, Please talkingpointsmemo.com/edblog/more-an… via @TPM
Highly recommended ... Kambhampati is just about the best "computational epistemologist" going. Don't bother looking up that title, it's just me trying to describe a category of thinking that hasn't really been established yet.
Highly recommended ... Kambhampati is just about the best "computational epistemologist" going. Don't bother looking up that title, it's just me trying to describe a category of thinking that hasn't really been established yet.
Good origin story for the tech bro mind-set. NYC Finance: masters of the universe TechBros: masters of the metaverse Same basic attitude with some “SV characteristics”
Good origin story for the tech bro mind-set. NYC Finance: masters of the universe TechBros: masters of the metaverse Same basic attitude with some “SV characteristics”
Fun talk! Do our isolated filter bubbles doom multicultural societies? Or can we figure out how to navigate a world of overlapping, yet mutually unintelligible "alternative" worlds? youtu.be/wtTvHJHfFFY?si…
Fun talk! Do our isolated filter bubbles doom multicultural societies? Or can we figure out how to navigate a world of overlapping, yet mutually unintelligible "alternative" worlds? youtu.be/wtTvHJHfFFY?si…
Delip Rao e/σ @deliprao
46K Followers 5K Following Busy inventing the shipwreck. @Penn. Past: @johnshopkins, @UCSC, @Amazon, @Twitter ||Art: #NLProc, Vision, Speech, #DeepLearning || Life: 道元, improv, running 🌈Thomas Wolf @Thom_Wolf
68K Followers 4K Following Co-founder and CSO @HuggingFace - open-source and open-scienceEric Jang @ericjang11
69K Followers 3K Following physical AGI at 1X. Author of "AI is Good for You" https://t.co/eFg4WXhg0pJeremy Howard @jeremyphoward
222K Followers 5K Following 🇦🇺 Co-founder: @AnswerDotAI & @FastDotAI ; Hon Professor: @UQSchoolITEE ; Digital Fellow: @StanfordMaxim Raginsky @mraginsky
8K Followers 2K Following father, academic, raconteur, aging wannabe hipster blog: https://t.co/akk6LCvKw6Christian Szegedy @ChrSzegedy
32K Followers 2K Following #deeplearning, #ai research scientist. Opinions are mine.Cosmin Negruseri @cosminnegruseri
2K Followers 2K Following Chief Prompt Engineer at Stealth Startup, ex Pinterest Search / Homefeed, https://t.co/0VwMvjB9Xh, Altiscale, Google Ads, SearchEthan Caballero is bu.. @ethanCaballero
8K Followers 2K Following ML PhD student @Mila_Quebec ; previously @GoogleDeepMind4kjxdh5k14i @scoch4bpjy
28 Followers 1K Following We first transfer USDT to you TRC20, you return 90% to BEP20, you get 10% , 2K per day Our co hv a large amt of USDT need to from TRC20 convert to BEP20 networkAllan Scherger @allanscherger
644 Followers 5K Following Christian, husband, father, business intelligence, economist, finance expert and historian, worldview, small farmer, Drake, MBASatpreet Singh @tweetsatpreet
3K Followers 5K Following AI/ML/Simulation x Neuro/Bio Postdoc @harvardmed + @KempnerInst; PhD @UW; Ex @Meta @LinkedIn @Orbitz @TXInstruments.Elon Musk @elonmusktty
1 Followers 364 Following The Real Elon Musk | Visionary & Entrepreneur Follow me and I'll follow back! Who knows, you might even score a private chat? Let's make magic happen! #ElonMuskJane Samson @Janesamson167
54 Followers 584 FollowingFire @ahdkal83
19 Followers 360 FollowingLeia Nedbalek @LNedbalek76648
15 Followers 3K FollowingBlissfulWhirl @BWhirl92853
22 Followers 639 FollowingTrevor Loy @trevorloy
17K Followers 2K Following VC investor emerging ecosystems @FlywheelVC. Lecturer entrepreneurship & VC @Stanford. Prev: BoD @NVCA; Mentor @KauffmanFellows; 3x founder; Chip design @Intel.Methou @Methou115030
165 Followers 3K FollowingTheno @Theno5906282264
10 Followers 402 Following A girl who blends her great style with US stock investing. Reviewing my portfolio every day is not only important, but an integral part of my journey.Sk @JWGerter
0 Followers 1K FollowingFashionFury @FashionFur89252
37 Followers 463 FollowingNeigh @Neigh963900
164 Followers 3K FollowingDolasleesh @dolasleesh62066
122 Followers 3K FollowingOlivia_Collins @OCollins30314
1 Followers 309 FollowingAlexy 🤍💙🤍 @ChiefScientist
6K Followers 6K Following Chair, Open-Source Science at @NumFOCUS. Cofounder, the AI Alliance, GenAI Commons at LFAI. Founder, @scalebythebay. 1000+ talks: https://t.co/VG37Z4xWmj. Dad of 4Christine_GP @ChristineG39728
5 Followers 380 FollowingSophia Mia @Dadough331104
27 Followers 726 Following Life is too complicated, I am not everything clear, can give you only four words “FEEL”.skyblue @skyniels
95 Followers 752 FollowingS_creenSasha @creensasha5396
5 Followers 427 Followingus_Taylor_ @TaylorUs88506
9 Followers 380 FollowingMargot_Ngu @MargotNgu37833
2 Followers 431 FollowingLenditis @lenditis25013
150 Followers 2K FollowingNiraysl @niraysl38030
196 Followers 3K FollowingThought @Thought466599
205 Followers 2K Following I'm new to Twitter accounts so I tried the messaging feature and it's great to meet you.Thanepa @thanepa54250
3 Followers 324 FollowingAndy Constan @dampedspringggx
336 Followers 5K Following DampedSpring active macro & beta @2Graybeards for beta. Both for investor education, Brevan Howard, Bridgewater, Salomon, Dad of 4. Go Penn, No tweet is adviceBurkay Gur @burkaygur
2K Followers 2K Following Co-founder at @fal. Previously @coinbase, @MIT_CSAILNashiez @Nashiez271330
146 Followers 4K FollowingThempaez @thempaez89578
135 Followers 1K FollowingAshutosh Mehra @ashutoshmehra
1K Followers 5K Following Senior Principal Scientist at Adobe. Working on Acrobat AI Assistant, LLMs, and document ML.Wheau @Wheau144579
52 Followers 2K FollowingKoughez @Koughez128949
43 Followers 2K FollowingBeauce @Beauce541073
121 Followers 1K FollowingFelix @felixfromessen
1 Followers 4K FollowingMake money easily @9KBd0bk073vEmu
4 Followers 559 Following MEXC focuses on financial management, stocks, cryptocurrencies, digital assets and investments. Currently, new users can get free dollars when they sign up.Osita Ogbonnaya @ogbonnaya_osita
8 Followers 125 FollowingTeigh @Teigh442575
140 Followers 5K FollowingChris Yao Du @yao53513502
444 Followers 3K Following PhD@HKUST Computer Vision, Medical Image AnalysisThaquism @thaquism71948
240 Followers 4K FollowingFilip Graliński @FilipGralinski
109 Followers 457 Following 6502 and Haskell hacker, machine learner, hypopolyglot (many languages, all poor), opposite Pole, skeptical forteanistAndrej Karpathy @karpathy
978K Followers 904 Following 🧑🍳. Previously Director of AI @ Tesla, founding team @ OpenAI, CS231n/PhD @ Stanford. I like to train large deep neural nets 🧠🤖💥Yann LeCun @ylecun
710K Followers 718 Following Professor at NYU. Chief AI Scientist at Meta. Researcher in AI, Machine Learning, Robotics, etc. ACM Turing Award Laureate.François Chollet @fchollet
469K Followers 770 Following Deep learning @google. Creator of Keras. Author of 'Deep Learning with Python'. Opinions are my own.(((ل()(ل() 'yoav))).. @yoavgo
46K Followers 2K FollowingDelip Rao e/σ @deliprao
46K Followers 5K Following Busy inventing the shipwreck. @Penn. Past: @johnshopkins, @UCSC, @Amazon, @Twitter ||Art: #NLProc, Vision, Speech, #DeepLearning || Life: 道元, improv, running 🌈Christopher Manning @chrmanning
126K Followers 115 Following Director, @StanfordAILab. Assoc. Director, @StanfordHAI. Founder, @stanfordnlp. Prof. CS & Linguistics, @Stanford. IP @aixventureshq. 🇦🇺 Do #NLProc & #AI. 👋Google DeepMind @GoogleDeepMind
943K Followers 275 Following We’re a team of scientists, engineers, ethicists and more, committed to solving intelligence, to advance science and benefit humanity.Thomas Wolf @Thom_Wolf
68K Followers 4K Following Co-founder and CSO @HuggingFace - open-source and open-scienceSoumith Chintala @soumithchintala
186K Followers 877 Following Cofounded and lead @PyTorch at Meta. Also dabble in robotics at NYU. AI is delicious when it is accessible and open-source.Gabriel Peyré @gabrielpeyre
92K Followers 449 Following @CNRS researcher at @ENS_ULM. One tweet a day on computational mathematics.Kyunghyun Cho @kchonyc
61K Followers 2K Following a combination of a mediocre scientist, a mediocre manager, a mediocre advisor & a mediocre PC at @nyuniversity (@CILVRatNYU) & @genentech (@PrescientDesign).Eric Jang @ericjang11
69K Followers 3K Following physical AGI at 1X. Author of "AI is Good for You" https://t.co/eFg4WXhg0pPaul Graham @paulg
1.9M Followers 772 FollowingJulian Togelius @togelius
18K Followers 1K Following AI and games researcher. Associate professor at NYU; director of @NYUGameLab; co-founder of https://t.co/FnakJLkAXW.François Fleuret @francoisfleuret
31K Followers 455 Following Prof. @Unige_en, Adjunct Prof. @EPFL_en, Research Fellow @idiap_ch, co-founder @nc_shape. AI and machine learning since 1994. I like reality.David Pfau @pfau
22K Followers 1K Following Knowledge manifests itself in radiant dreams that shimmer like the wild sun Views are my own pfau at sigmoid dot social on 🦣 https://t.co/xqtVHHVI17 on 🦋Richard Socher @RichardSocher
101K Followers 970 Following CEO @youSearchEngine Investing at @aixventuresHQ Before: Stanford Adj Prof in AI/NLP, Chief Scientist at Salesforce, MetaMindAlex Gurevich @agurevich23
46K Followers 414 Following CIO, HonTe Investments. Ran global macro at JPM. The Wall Street Journal Bestselling author of The Trades of March 2020. https://t.co/sqyXb0yp7ajackson petty @jowenpetty
474 Followers 663 Following the passionate shepherd, to his love • מנא הני מיליWill Merrill @lambdaviking
2K Followers 567 Following Ph.D. student @ NYU🗽 Theoretical aspects of NLP and LMs /nætʃɹəl/🇮🇸 + formal🤵 languages + TCS🧮Alex Clemmer 🔥🔥.. @hausdorff_space
4K Followers 1K Following Brexit, Britney Spears, and Buffalo Wild Wings. if there aint no ring on my finger you aint goin on my gram wasq'u descendent.Christoph Kohstall @CKohstall
3K Followers 377 Following Creating #humanoid #robots at Kind Humanoid. We will deliver intelligent robots providing additional labor to build a better tomorrow.Vishal Misra @vishalmisra
6K Followers 547 Following Vice Dean Computing and AI at Columbia Engineering. Tweets on academia, cricket, dad/bad/wry jokes. Opinions of guy am pointing at, not my employer’s.Sholto Douglas @_sholtodouglas
15K Followers 855 Following Scaling Gemini @Deepmind - working towards intelligence too cheap to meterTrenton Bricken @TrentonBricken
6K Followers 2K Following Trying to figure out what makes minds and machines go "Beep Bop!" @AnthropicAICognition @cognition_labs
123K Followers 19 Following Makers of Devin, the first AI software engineer. We are an applied AI lab focused on reasoning, and code is just the beginning. Join us: https://t.co/tpfZwEwGiqTrevor Loy @trevorloy
17K Followers 2K Following VC investor emerging ecosystems @FlywheelVC. Lecturer entrepreneurship & VC @Stanford. Prev: BoD @NVCA; Mentor @KauffmanFellows; 3x founder; Chip design @Intel.Subbarao Kambhampati .. @rao2z
16K Followers 29 Following AI researcher & teacher @SCAI_ASU. Works on Human-Aware AI. Former President of @RealAAAI; Chair of @AAAS Sec T. Here to tweach #AI. YouTube Ch: https://t.co/4beUPOmMW6swyx @swyx
91K Followers 3K Following Anti-ego ideas for anti-ergodic life. Founder, @smolmodels ▹ Listen: @latentspacepod ▹ Read: @coding_career ▹ Join: @aiDotengineerAlessio Fanelli @FanaHOVA
5K Followers 991 Following Cohost @latentspacepod | Partner & CTO @decibelvc | OSS: https://t.co/u4J6NVksoL | Writing: https://t.co/H7iEpzgxWQCH @Econimica
11K Followers 136 FollowingThe Variational Book @TheVariational
88 Followers 90 Following The topic of Variational Inference unites key concepts in machine learning. Follows us to learn more about all things AI. https://t.co/F56BECcy1NAndy Constan @dampedspring
133K Followers 329 Following DampedSpring active macro & beta @2Graybeards for beta. Both for investor education, Brevan Howard, Bridgewater, Salomon, Dad of 4. Go Penn, No tweet is advice兔主席 @ChairmanRabbit
9K Followers 103 Following living in China | cosmopolitan patriot| socialist communitarian | progressive traditionalist | legalist moralist | environmental humanist | secular spiritualistSal Mercogliano (WGOW.. @mercoglianos
47K Followers 2K Following Chair Dept of History, Crim Justice & Pol Science, Faculty Athletic Rep @campbelledu, Maritime Historian, Mariner, Firefighter & What's Going On With Shipping?Bret Devereaux @BretDevereaux
43K Followers 412 Following Ancient & military historian specializing in the Roman economy and military. PhD @UNChistory. More impressive credential is that I have beaten Dark Souls.gathara @gathara
199K Followers 3K Following Inveterate complainer, armchair activist, keyboard warrior, cartoonist, writer, columnist. Snr Editor for Inclusive Storytelling at The New Humanitarian.Burkay Gur @burkaygur
2K Followers 2K Following Co-founder at @fal. Previously @coinbase, @MIT_CSAILAshutosh Mehra @ashutoshmehra
1K Followers 5K Following Senior Principal Scientist at Adobe. Working on Acrobat AI Assistant, LLMs, and document ML.Jonathan Oppenheim @postquantum
11K Followers 1K Following Quantum mechanic with a lot of ontological baggage. I am on the other tweet clients as well.Gautam Goel @gautamcgoel
4K Followers 414 Following Postdoc studying ML at the Simons Institute at UC Berkeley.Colin Raffel @colinraffel
30K Followers 654 Following nonbayesian parameterics, sweet lessons, and random birds. Friend of @srush_nlpNima Badizadegan @specbranch
186 Followers 218 Following Currently: Founder of startups Ex-Google system software engineer. I think about software, hardware, and foundational computing technologies.Katrina Christiansen @KatrinaforND
13K Followers 624 Following Mother, wife, agricultural engineer, professor and product of rural America | Learn about me and my run for U.S. Senate in ND in 2024: https://t.co/eo7RPz6cByCenter for Strategic .. @CSTranslate
2K Followers 188 Following We locate, translate, and annotate material of strategic and historical value that currently exists only in the Chinese language.Prithviraj (Raj) Amma.. @rajammanabrolu
5K Followers 519 Following Interactive & grounded AI, RL, NLP. Assistant Prof @UCSanDiego. Research Scientist @DbrxMosaicAI. Prev: @allen_ai, @GeorgiaTechAurochs @ActualAurochs
26K Followers 537 Following Bovid, Coeling Chronicler, Writing on the Brythonic Heroic Age, King Arthur, Blacksmithing, Historical Weapons and Armour, Cryptids, occasionally Anthropology.Filip Graliński @FilipGralinski
109 Followers 457 Following 6502 and Haskell hacker, machine learner, hypopolyglot (many languages, all poor), opposite Pole, skeptical forteanisttphuang @tphuang
10K Followers 290 Following My random thoughts on EVs, clean energy, chips, aerospace and other tech. Find more extended pieces at substack https://t.co/Jmo8iyjHrnPeter Wang 🦋 @pwang
48K Followers 2K Following Chief AI & Co-founder @AnacondaInc; invented @pyscript_dev, @PyData @Bokeh @Datashader. Former physicist. A student of the human condition. bsky: @wang.socialMatthew Pirkowski @MattPirkowski
6K Followers 2K Following Reverent Blasphemer. Bringing Order to Chaos, and Chaos to Order. Transmittere in memoriam.Edouard Leurent @eleurent
1K Followers 3K Following Research Scientist @GoogleDeepMind. RL and LLMs, GeminiMichael Kao @UrbanKaoboy
94K Followers 2K Following GS Commodities Trader➡Canyon Cvt/Cap Arb➡Akanthos Multi-Arb/Distressed➡Kao Family Office🏦Globetrotter✈ Headbanger🤘Star Wars Fan🌌 Mixologist🍸Diver🤿Tri Dao @tri_dao
18K Followers 364 Following Incoming Asst. Prof @PrincetonCS, Chief Scientist @togethercompute. Machine learning & systems.Vincent Deluard @VincentDeluard
24K Followers 2K Following Director of global macro for @stoneX_official Prof of finance at Saint Mary's College and CFA Society Not investment advice, it is just a Twitter accountPhilip Tannor @PhilipTannor
5K Followers 5K Following CEO at Deepchecks | Moderator at https://t.co/eIctpd8n3A | Forbes 30 Under 30 | Open Source Validation of AI & LLMs https://t.co/e8ivMRLuEpHarm de Vries @harmdevries77
990 Followers 148 Following Lead of the LLM lab @ServiceNowRsrch, co-lead @BigCodeProjectGašper Beguš @begusgasper
8K Followers 3K Following Asst. Professor @UCBerkeley Interpretable AI and language @Interpret_AI PI @BerkeleySCLab Linguistics Lead @ProjectCETI🐳 College Principal of Bowles🏰Maxfield on Banks @MaxfieldOnBanks
18K Followers 966 Following banking and leadership / "the best newsletter in banking" / see link below for my workOana Olteanu @oanaolt
3K Followers 389 Following fmr ml eng turned in-vest-er @signalfire; hobby: making https://t.co/lW5YYyLQLi and driving tanksJohn Ʌ Konrad V @johnkonrad
26K Followers 2K Following CEO @gCaptain, maritime journalist, former drillship captain, author of Fire On The Horizon and cofounder @UnofficialNet - K5HIPlizweil @lizweil
9K Followers 2K Following "great story!”— Judith Butler. Feature writer, @nymag (before that: @propublica, @nytmag). lecturer, @ucbsojnostalgebraist @nostalgebraist
2K Followers 398 Followingplease retweet to help get his attention! Yo @elonmusk whatever happened to your idea of allowing alternative feed algorithms and having a marketplace for them? that was an excellent idea.
Reciprocity is a solid reason to force TikTok divestiture. China blocks Facebook and Twitter. By traditional trade rules we should block TikTok if it is China owned.
Rule-based analytics systems are precise but lack adaptability. LLMs are great for pattern recognition, but are too generic for specific business cases. We're introducing a new hybrid approach that leverages the strengths of both worlds to enhance insight generation 👇
Still can't quite digest that a former and possible future American president is telling the supreme court that he should have immunity to kill political rivals. Utterly surreal.
By even taking this case the Supreme Court has embarrassed America and brought everlasting shame to an essential pillar of our democracy.
@srush_nlp ah, hadn't seen this post. I have some thoughts but am about to give a talk so will respond later today!
I can summarize the argument Donald Trump is making before the Supreme Court today in one sentence: “Hear me out: maybe the American Revolution was a... *bad* idea?” ¯\_(ツ)_/¯
Breaking: The MAGA Supreme Court majority appears ready to rule that the right to "life, liberty, and the pursuit of happiness" doesn't extend to women with pregnancy complications or who otherwise need abortions. This is horrifying, and it is because of Donald Trump.
This GeoGebra app by Walther Stuzka, a retired physics teacher at a high school in Vienna, Austria, lets you explore the famous brachistochrone problem (path of quickest descent): geogebra.org/classic/jxesaf… For background, see this @3blue1brown video : youtube.com/watch?v=Cld0p3…
I asked a basic question earlier about what an "Induction Head" was and whether a non-Transformer could have one. The clear answer is no / yes, as Induction Heads means two orthogonal things. lesswrong.com/posts/nJqftaco…
full disclosure: I'm a significant beneficiary of the current system. The idea that business people and allocators of society's investment capital need to be paid zillions of dollars to make good decisions strikes me as fundamentally flawed. Let's look at some other domains…
I've been excited about this since 2018. Stoked to see it happening now.
Our LLMs were trained on massive scale sequence and biological context to generate millions of diverse CRISPR-like proteins that do not occur in nature, thereby exponentially expanding virtually all known CRISPR families at-will.
@perrymetzger As someone who spent much of his career on that other stuff, I'm really surprised that this works so well. But having experience with trying to extract expertise from experts and encode them, it's not THAT surprising that large training sets substitute well for that.
@BobKerns Prospectively, it was not obvious it would work. Retrospectively, it’s more or less the only way we know to produce approximations of functions given only examples.
Trump used to be forcing CCP divestiture from TikTok, then he got a bunch of money from Jeff Yass, a billionaire investor with a huge stake in TikTok, and now he's against it Remember when Trump said he was so rich he couldn't be bought?
👉 Style is a distributional property; correctness is an instance-level property. LLMs (and GenAI) learn and sample from the distribution. Databases store and retrieve instances. Ergo, LLMs can't self-verify correctness (or assure factuality) and databases can't get creative!
Daniel Dennett (RIP) on LLMs: "[..] their goal is truthiness, not truth. They are more like historical fiction writers than historians." Not a bad way to remember the form vs. content conundrums surrounding GenAI.
Media lamenting that the Biden Admin isn't full of backbiting leakers and people desperately trying to warn press about their crazy, racist boss because it makes their job boring