Dermal Cell News @DermalCell
An online resource for researchers studying dermal tissue. Part of the @STEMCELLTech Science News service. dermalcellnews.com Joined February 2015-
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Inducing co-stimulatory immune checkpoint CD137L expression in #melanoma cells enhances T cell-mediated anti-tumor immunity, reports a team from Central South University. 🔓 Read their findings in @NatureComms: go.nature.com/42d9Lkw
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The PAI-1 inhibitor TM5614 has demonstrated promising activity in early clinical studies, particularly in anti-PD-1-refractory #melanoma, and is currently under evaluation in multiple Phase II/III trials. Learn more about PAI-1 in skin malignancies. 👇 bit.ly/4nW8ZAL
Congratulations @DrPreetiSahuPhD, Drs. Sánchez-Danés, @EdouardHannezo, and team! 😁 In @NatureComms, they identify a relationship between cell shape and long-term clonal dynamics, which was validated during #BasalCell carcinoma initiation. Read it here: go.nature.com/4gHDdoB
Dr. @Muzz_Haniffa led this @NatImmunol study constructing a spatially resolved atlas of human skin #fibroblasts from healthy skin and 23 skin diseases, with comparison to 14 cross-tissue diseases. | @sangerinstitute 🧬Check it out here: go.nature.com/48ArMNs
The authors review endogenous and exogenous factors triggering cell cycle arrest in #DermalFibroblasts and their underlying molecular mechanisms, with a particular focus on the roles of key signaling pathways such as p53, TGF-β/Smad, and Wnt/β-catenin. 🔗 bit.ly/4npuRVe
👨⚕️👩⚕️ Recently in @emboreports, Drs. Sandra Iden and Carole Luthold report that extrinsic cues exert substantial effects on #melanocyte function, involving ERK-dependent MITF regulation. 📚 Check out the study out of @Saar_Uni: bit.ly/3VZFFxc
Employing medicinal chemistry, @NUSingapore scientists identified a more potent derivative termed Np75-4A22 that blocked nerve growth factor (NGF)-mediated #melanoma invasion at sub-micromolar concentrations. Read about the novel small molecule. 👇 bit.ly/4gKrFBa
Individuals with aberrant cholesterol production, especially those affected by primary cicatricial #alopecia, endure a lasting hindrance in hair regrowth stemming from the irreversible damage to their hair follicles. 💡 Learn more in @PLOSONE: bit.ly/3Ii1F3h
Dr. Maria Genander's team at @karolinskainst exploit the stereotyped hair follicle development to delineate the function of PADI4, an enzyme converting peptidylarginine to citrulline. 💇 Learn more in @ScienceAdvances: bit.ly/47PYwC1
This story explores the features and underlying mechanisms of various types of selective #autophagy and highlights their implications in burn injury and wound healing. 🩹 👀 Don't miss it: bit.ly/4pKVOV9
Hot of the press from the @AgostinisLab! Researchers show that BDH2 is a key effector of inter-organelle Fe(II) redistribution and ferroptosis vulnerability during melanoma transition from a melanocytic to a mesenchymal-like phenotype. @NatMetabolism go.nature.com/46a6Dbv
This work presents a robust, biocompatible lipid nanoparticle platform with minimized immunogenicity and strong potential for genome-editing therapies in inflammatory conditions. 🔥 Check out their murine #psoriasis model: bit.ly/4mmIinE
🥼 Researchers elucidated the effects and potential mechanisms of human YKL-40 antibody on #AtopicDermatitis-affected skin. Check it out! 👉 bit.ly/4nl8yzw
📖 Dr. @EmmaGuttman and scientists at @IcahnMountSinai provide an overview of #AtopicDermatitis pathogenesis driven by T-cell imbalance and describe a novel therapeutic option targeting the OX40 receptor. @DermatolTher | bit.ly/4njmTwm
💡 Scientists at @UniFAU provided insights into the functional role of ARHGAP29 and its downstream signaling in #melanoma. They found evidence supporting the hypothesis that ARHGAP29 is an important player in melanoma progression. @MolOncology | bit.ly/4gkLJd5
🔬 Dr. Varuna Nangia and team at @CUBoulder found that mTORC1-mediated increases in the amount of the cell-cycle protein cyclin D1 drove escape from standard BRAF and MEK inhibitors in cultured BRAF-mutant #melanoma cells. @scisignal | bit.ly/4npzi22
🔬 The authors examined how selenomethionine affects #keratinocyte proliferation and migration using cell proliferation and scratch assays. An ICR mouse skin wound model was established to evaluate healing capacity. 🔗 bit.ly/3I7RQVs
LZTR1 is a “safeguard” for #melanoma cells under stress and its downregulation can be exploited for melanoma therapy. | @YaleMed Learn more from Drs. Sarah Slavoff, Ruth Halaban, and team. 👇 📚 Get the full story in @oncogenejournal: go.nature.com/4mSRIbA
Novel small molecules inhibited the manifestation of malignant phenotype by inhibiting the Wnt/β-catenin signaling of human cutaneous squamous cell carcinoma cells. 🙌 Check it out in @JExpMed | go.nature.com/3I4C8KG
🥼 Drs. Iman Osman, Markus Schober, and colleagues reveal a connection between NF1 loss and increased EGFR expression that is critical for the survival and growth of NF1-mutant #melanoma cells in patient-derived culture and xenograft models. | @CR_AACR bit.ly/3HEI6C0
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461 Followers 284 Following ＊化粧品成分の研究のために大学院進学 ＊現在は講師業（専門：生物） ＊「丸暗記にならない化粧品知識」をお届け！ ＊化粧品の知識を小中学生の理科からわかりやすくお伝えしていきます ＊お仕事はDMまで
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Center for Cancer Res... @cancerCCR
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Higgins Lab @HigginsBioeng
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Sarthak Sinha, MD, Ph... @sarthak_s
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554 Followers 454 Following We are a research lab of skin biology enthusiasts led by @GernotWalko, fascinated about stem cells, skin cancer and Hippo signalling. All opinions our own.
Extracellular Matrix ... @ExtracellMatrix
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LEO Foundation - LEO ... @LEOFondet
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Paul Knoepfler @pknoepfler
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Molecular Medicine - ... @MolMedBMC
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Dr. Lindsay Kalan �... @lindskalan
782 Followers 904 Following Associate Professor @BBS_McMasterU and @UWMadisonMMI interested in microbes and how they interact with each other and with us.
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238 Followers 172 Following Burns & Trauma (IF 5.099）is a peer-reviewed journal publishing the latest developments in basic, clinical and translational research related to burns.
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420 Followers 129 Following A world leading open access journal from @BioMedCentral, part of @SpringerNature, covering the interface of medicine and biology with nanoscale sciences.
Erin Jimenez @ErinJimenezPhD
1K Followers 945 Following assistant professor @JohnsHopkins | hair cell regeneration | pugilist @levelupboxing | IG thejimenezlab |she/her
Vítor Gaspar @Gaspar_Vm
2K Followers 5K Following Assistant Professor @UnivAveiro CICECO - Institute of Materials @Compass_RG #TissueEngineering #LivingMaterials #InVitroModels #Cancer #Nanomed #Bioprinting
Kiarash @kiakho
605 Followers 170 Following Dermatologist, Happy dad, skin stem cell and skin cancer scientist
Panagiota Filippou @PanagiotaFilip3
264 Followers 667 Following Associate Professor, School of Medicine, Aristotle University of Thessaloniki. Clinical Biochemist with a focus in cancer research.
Shook Lab @ShookLab
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BF @Biofabrication
2K Followers 533 Following The leading journal in bioprinting and bioassembly. Journal Impact Factor 9 https://t.co/x9hwVr2nL4
Siqi Liu @siqi_liu_
383 Followers 192 Following Biochemist at heart, has a deep interest in understanding innate immune regulation of tissue injury repair. Assistant Prof. at UT Southwestern
Patricia P Centeno @PPCenteno22
214 Followers 533 Following Postdoctoral Researcher at Sansom Lab Beatson Institute @CRUK_BI | #Specificancer #GrandChallenge #science #skincancer #melanoma #cscc |#womeninSTEMTrends for United States
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