Science Signaling @scisignal
Uncovering mechanisms in biology, gaining insights into physiology and disease. science.org/journal/signal… Washington, DC Joined April 2010-
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A recent study reveals how a cytokine cocktail used to activate natural killer cells for cancer #immunotherapy invigorates their antitumor abilities through a twin-pronged molecular pathway, potentially informing future clinical applications. @CIRI_Lyon scim.ag/3K49WZb
In this week’s Editors’ Choice piece, we highlight a study by Kaul and colleagues in @NatMetabolism, showing that the whitening of brown fat driven by mitochondrial stress involves reduced nuclear stiffness. Read more in #ScienceSignaling: scim.ag/4numAzw
Our gut microbiome and its metabolites have much more impact than anticipated —Enhancing the response to amphetamines science.org/doi/10.1126/sc… —Motivating exercise and shaping performance nature.com/articles/s4158… —Driving sugar craving nature.com/articles/s4156……
Why does TIM3 inhibit T cell signaling in vivo, but stimulate it in vitro? Using tumor-derived spheroids, a team shows that TIM3 can amplify either inhibitory or stimulatory signals depending on the surrounding 2D or 3D cellular context. @CMMBristol scim.ag/4271Sgs
Examining naïve T cells exposed to activin A, scientists show that nonpathogenic T helper 17 cells display metabolic alterations such as reduced reliance on glycolysis, which depended on a pathway involving adenosine and AMPK. @BRFAA_IIBEAA scim.ag/3W4vCqB
In a new study, scientists show that wild-type members of the RAS family of proteins can support the cancer-causing activities of mutant RAS proteins, which are implicated in various malignancies. @KortumLab @USUhealthsci scim.ag/4mpIP8j
A new study reveals how a cytokine cocktail used to activate natural killer cells for cancer #immunotherapy invigorates their antitumor abilities through a twin-pronged molecular pathway, potentially informing future clinical applications. @CIRI_Lyon scim.ag/3K49WZb
A recent study has uncovered how the contents of extracellular vesicles can interact with proteins that #HIV relies on to replicate—findings that may lead to new therapeutics to suppress or even eradicate HIV infection. @OkeomaLab @NYMC_PMI scim.ag/4piPhkb
A bacterial member of the gut #microbiome can shape the rewarding properties of #amphetamine drugs and their effects on male sexual motivation, according to research in fruit flies that uncovers a new gut-brain connection. @GallivantLab @UABSurgery scim.ag/4ggBSoo
New findings in vitro highlight the contribution of wild-type RAS family members to mutant RAS–driven #cancer development, underscoring the need for more RAS family–targeted approaches to slow the growth of tumors in patients. @KortumLab @USUhealthsci scim.ag/4mpIP8j
This week, researchers demonstrate that #mTORC1 is a critical player that supports the ability of IL-15 and IL-18 to enhance the activation of natural killer cells, showing that each cytokine acts through distinct but synergistic pathways. @CIRI_Lyon scim.ag/3K49WZb
A preclinical study interrogates how a cytokine cocktail can invigorate cancer-fighting natural killer cells, new experiments reveal how the oncogenicity of RAS is a family affair, and more in the new issue of #ScienceSignaling. scim.ag/4nybkBJ
A new study has uncovered how the contents of extracellular vesicles can interact with proteins that #HIV relies on to replicate—findings that may lead to new therapeutics to suppress or even eradicate HIV infection. @OkeomaLab @NYMC_PMI scim.ag/4piPhkb
A bacterial member of the gut #microbiome can shape the rewarding properties of #amphetamine drugs and their effects on male sexual motivation, according to research in fruit flies that uncovers a new gut-brain connection. @GallivantLab @UABSurgery scim.ag/4ggBSoo
New experiments have uncovered how #melanoma and other types of cancer cells can evade therapies by relying on a cell cycle protein—a discovery that could inform more effective combination therapies for these hardy tumors. @BioFrontiers scim.ag/3HTvS8D
A preclinical study identifies a mechanism behind the opioid paradox—where the long-term use of opioids leads to pain sensitivity—and hints that targeting this pathway may inform safer and more effective use of #opioids in pain management. @MDAndersonNews scim.ag/4naD7rG
In this week’s Editors’ Choice piece, we highlight a study by Shvetcov and colleagues in @NatureMedicine, showing how an APOE variant dysregulates immunity, leading to neurodegenerative disease. Learn more: scim.ag/46jRxPg
Researchers identify proteins in semen- and plasma-derived extracellular vesicles that interact with the HIV transactivator Tat and host NF-kB, as well as larger networks of transcriptional, RNA-processing, and epigenetic regulators. @OkeomaLab @NYMC_PMI scim.ag/4piPhkb
The commensal microbe #Fusobacterium supports the rewarding properties of amphetamines by increasing dopamine transporters in the brain through an epigenetic mechanism involving the fatty acid butyrate, shows work in fruit flies. @GallivantLab @UABSurgery scim.ag/4ggBSoo

Cancer Cell @Cancer_Cell
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FrezzaLab @FrezzaLab
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Science Immunology @SciImmunology
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BryanRoth @zenbrainest
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The Journal of Immuno... @J_Immunol
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Francis @francis_eseh
62 Followers 1K Following Mathew 6:33||🇨🇲. https://t.co/6V5UKV0fiA https://t.co/fLp0AhniyF.
superior engineering ... @awards86226
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Usama Ashraf, PhD @Leone1523
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318 Followers 2K Following @JGokuRobinson @andersen_inger @xai https://t.co/OBdGyNeYm8 @wef @UN @Grimezsz @czbiohub @X @TheODINInc @VaclavSmil @GlobalFund @geochurch @michiokaku @WHO
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Cansümer سوليم�... @21Canslymn
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Arch Biopartners Inc @archbiopartners
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William Pappas @will44395
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The School of Hermito... @theschoolofher
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Abhisar G. Mehta @5258c79d2d73491
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NonsenseOmnibus @NonsenseOmnibus
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Hannah Sues @HannaHSueS87
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eLife - the journal @eLife
172K Followers 709 Following The funder-researcher collaboration and open-access journal for research in the life and biomedical sciences | @eLifeCommunity
Nature Metabolism @NatMetabolism
79K Followers 273 Following Nature Metabolism publishes studies that advance our understanding of metabolic and homeostatic processes in physiology and disease.
Molecular Cell @MolecularCell
143K Followers 524 Following Molecular Cell is a Cell Press journal that aims to publish the best papers in molecular biology.
FrezzaLab @FrezzaLab
27K Followers 3K Following We are a group of metabolism-lovers, focused on mitochondrial metabolism. Tweets are from Christian. https://t.co/EbWsJo6DnZ
Science Immunology @SciImmunology
64K Followers 525 Following Official twitter account for the journal Science Immunology. Also find us on Facebook: https://t.co/sndJBQOvbR
Cell Metabolism @Cell_Metabolism
54K Followers 470 Following Cell Press journal publishing cutting-edge research in metabolism biology, from molecular/cellular biology to translational and clinical studies.
Immunity @ImmunityCP
70K Followers 325 Following Cutting-edge research in immunology from around the world. This account is no longer monitored, and content is automated. Join us on BlueSky!
Nature Medicine @NatureMedicine
352K Followers 255 Following Nature Medicine is a research journal devoted to publishing the latest advances in translational and clinical research for scientists and physicians.
Journal of Cell Biolo... @JCellBiol
53K Followers 950 Following The Journal of Cell Biology (JCB) publishes peer-reviewed research on all aspects of cellular structure and function. Est. 1955 - @RockUPress
Nature Rev Immunol @NatRevImmunol
69K Followers 965 Following We publish immunology reviews. Find us here too: https://t.co/IrscA6xKVA
Journal of Experiment... @JExpMed
34K Followers 1K Following The Journal of Experimental Medicine publishes immunology, cancer, stem cells, microbial pathogenesis, vascular biology, neurobiology. Est. 1896 - @RockUPress
BryanRoth @zenbrainest
17K Followers 580 Following James Black: 'the prismatic qualities of the assay distort our view in obscure ways and degrees'
Nature Communications @NatureComms
248K Followers 487 Following Nature Communications is an open access journal publishing high-quality research in all areas of the biological, physical, chemical and Earth sciences.
Ivan Zanoni @Lo_Zanzi
9K Followers 159 Following Associate Professor at Harvard Medical School, in love with a red-haired beautiful woman, his kids... and immunology. He/him/his. 🇮🇹 🇺🇸 Views my own.
Science Translational... @ScienceTM
34K Followers 270 Following The mission of Science Translational Medicine (AAAS) is to promote human health by communicating leading research and policy in biomedicine.
Nature Reviews Cancer @NatureRevCancer
75K Followers 1K Following Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
Jonathan Kagan @jkagan1
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Science Advances @ScienceAdvances
66K Followers 101 Following Science Advances is an open access journal from AAAS that publishes innovative original research across all disciplines of science freely to a global audience.
Delgoffe Lab @DelgoffeLab
7K Followers 394 Following Cancer Immunometabolism - Professor - Director: Tumor Microenvironment Center - @PittTweet @UPMCHillmanCC - CoFounder:Novasenta - EiC:Immunology - views my own
Nature Cell Biology @NatureCellBio
124K Followers 615 Following A journal dedicated to publishing the latest advances across all areas of cell biology.
Eric J. Nestler, MD, ... @EricJNestler
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Arun K. Shukla @arshukla
11K Followers 125 Following Professor and Sonu Agrawal Memorial Chair, IIT Kanpur Senior Fellow, DBT Wellcome Trust India Alliance सपने देख रहीं जो आँखें, मैं उन में साहस भरता हूँ।
Science Robotics @SciRobotics
28K Followers 356 Following Official Twitter account of the journal Science Robotics. Also find us on Facebook: https://t.co/EI6szHLWIb
Christie Wilcox @NerdyChristie
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Sudip Parikh @sudipsparikh
2K Followers 443 Following optimistic scientist with privilege of leading @AAAS & executive publisher of @sciencemagazine Views here are mine not necessarily AAAS RT≠agreement
@scipak_es @scipak_es
3K Followers 1K Following Oficina de prensa de la familia de @ScienceMagazine @ScienceTM @SciSignal @ScienceAdvances @SciImmunology @SciRobotics Contacto: [email protected]
Holden Thorp, dormant... @hholdenthorp
18K Followers 1K Following No longer posting here. Find me at https://t.co/fAOi2LCf08 and link below for other platforms.
Valeria Sabaté @SabateValeria
387 Followers 2K Following Latina, immigrant, scicomm. Sr. Media & Public Affairs Mgr @aaas. Creator of @scipak_es at @ScienceMagazine. @JohnsHopkins alumna. Prior @ChildrensNatl
Science Visuals @ScienceVisuals
10K Followers 148 Following Follow @ScienceMagazine to see the latest graphics and visualizations from the Science Visuals team.
Avinash Shenoy @avi_cmbi
2K Followers 467 Following Reader in Innate Immunity & Infection at Imperial College London. Tennis fan. He/him.
Prof Patrick Eyers @Pseudoenzyme
1K Followers 1K Following Head, Dept of Biochemistry, Cell and Systems Biology, University of Liverpool. Protein kinases, pseudokinases, pseudoenzymes and Broncos fan. Views are personal
Jeremy Smyth @SmythLab
280 Followers 880 Following Cell bio lab at Uniformed Services University. We like calcium signaling, and links between the ER and microtubules. And flies.
Tanya Freedman (Forme... @tfreedmanlab
446 Followers 408 Following Find me at tfreedmanlab dot bsky dot social Associate Prof, Dept of Pharmacology & Center for Immunology, UMN
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Maini Lab UCL @maini_lab
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Newton Lab @NewtonLab
688 Followers 141 Following The Newton Lab is led by Alexandra Newton, Department of Pharmacology @UCSanDiego. Tweets are her own.
Iannis Aifantis @iannisaifantis1
10K Followers 1K Following Cancer & Immunology Research. Professor & Chair, @NYUGSOM_Path @nyugrossman. All opinions are my own only. Visit me also on @instagram and @LinkedIn.
Gary Siuzdak @kadzuis
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Benjamin Parker @Ben_Leo_Parker
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Soragni:Lab @soragnilab
7K Followers 898 Following Of aggregation, rare cancer biology and organoids Associate Prof @UCLA Board @TheSFPM https://t.co/wjdj4V5zzV
Thomas Vierbuchen @TommyVierbuchen
1K Followers 1K Following Dev Bio Program + Center for Stem Cell Biology @MSKCancerCenter. Building next-gen cellular models to characterize polygenic basis of neurological disorders.
Dana-Farber @DanaFarber
112K Followers 9K Following Dana-Farber Cancer Institute - a leading center for expert, compassionate cancer care and advanced research. Appts: 877-442-3324 | https://t.co/HvCwkLltic
U-M Rogel Cancer Cent... @UMRogelCancer
7K Followers 2K Following The University of Michigan Rogel Cancer Center is committed to improving the health and well-being of people with cancer. Part of @umichmedicine. #GoBlue
Midwinter Conference ... @Midwinter_Immun
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Joe W. Ramos, PhD @joewramos
665 Followers 1K Following President & CEO @the_Lundquist | Championing biomedical innovation & research to improve health worldwide 🌍 | #BiomedicalInnovation #Leadership | https://t.co/RQGF8VskiZ
College of Chemistry @UCB_Chemistry
12K Followers 373 Following UC Berkeley College of Chemistry. Advancing society through education and research.
Laboratorio de Bioqu�... @LLipidos
261 Followers 122 Following Facultad de Medicina, UdelaR, Uruguay. Espectrometría de masa para análisis lipidomicos en procesos inflamatorios y patología humana.
Saeid Ghavami @CellAutophagy
906 Followers 1K Following Associate Professor in University of Manitoba, Associate Editor (AE) BBA Mol Basis of Disease, AE Biochem. Biophysics Reports, AE MBEC
Pedro Beltrao @pedrobeltrao
7K Followers 1K Following Associate professor at ETH (@IMSB_ETH) studying the cellular consequences of genetic variation. Part of @theLoopZurich.
Jason Mercer @MercerLab
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Hsieh Lab @HsiehLab
2K Followers 616 Following A lab @FredHutch obsessed with translation control and its impact on health and disease. #mRNAtranslation #prostatecancer #bladdercancer #physicianscientist
FoxLabDuke @FoxLabDuke
1K Followers 573 Following The biology of genomic extremes: extra chromosome sets (polyploidy) and genes with rarely used codons. We study this in organ development and regeneration.
Mark Headley Lab @headleylab
640 Followers 254 Following Our lab at the Fred Hutch is focused on understanding the unique impact of the immune system on cancer metastasis to the lung.
Paul Humphries @PaulHumpa
3K Followers 4K Following Scientist with expertise in medicinal chemistry, phenotypic drug discovery, GPCRs, circadian rhythms & CNS/cancer/metabolic diseases. Stanford IMA & ChEM-H
Payam A. Gammage @mito_oncogene
2K Followers 278 Following Group Leader @CRUK_SI. Mitochondrial genetics, genome engineering, cancer metabolism. Lab supported by CRUK, ERC & NCI. EMBO 'Young' Investigator.
Jan Claesen @claesengroup
1K Followers 1K Following Associate Staff/Professor @CCLRI @ClevelandClinic. Account sleeping - now active on Bluesky https://t.co/ybmXIz8Z5i
UCSD Biodynamics Lab @UCSD_BDL
166 Followers 189 Following Lab of Jeff Hasty and Lev Tsimring. Synthetic Biology & Quantitative Biology
Ubiquitin & Cell Sign... @UCSLabUB
195 Followers 177 Following Research lab especialised in Large HERC family of HECT Ubiquitin E3 Ligases. Department de Ciències Fisiològiques. Universitat de Barcelona & IDIBELL Bellvitge.
Hamerlik’s Lab @HamerlikB
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Urszula McClurg 🇺�... @UrszulaMcclurg
1K Followers 978 Following PI interested in all things cilia, centrosome and germ cell cancer genes also a raging feminist.
Saez-Rodriguez Group @saezlab
5K Followers 560 Following Account of the Saez-Rodriguez lab at Heidelberg University Lab members tweet about our news, activities & publications Also at: https://t.co/YFqkPcH6dY
Felicia Goodrum🇺�... @GoodrumVirusLab
3K Followers 469 Following scientist/virus enthusiast/mother/advocate and lover of the natural world and truth and integrity
Ana Fernandez-Sesma @SesmaLab
9K Followers 572 Following Innate immune modulation by dengue virus and other viruses. 🪑 of 🦠. Family, Friendships, Mentoring and Science. Views my own
Fantauzzo Lab @Fantauzzo_Lab
960 Followers 998 Following We study receptor tyrosine kinase signaling in mammalian craniofacial development @CUAnschutz.
Stephanie Moon @smslmoon
2K Followers 2K Following Studying RNA regulation in stress & neurological disease. Assistant Professor at University of Michigan @umichrna @UM_Genetics @NIH_LRP #raredisease
Pasare Lab @ThePasareLab
480 Followers 42 Following Welcome to the Pasare Lab at CCHMC. Our lab studies TLR signaling pathway and how activation of TLRs influence the shaping of the adaptive immune responses.