Jake Freimer (@[email protected]) @JakeFreimer

Joined July 2013

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192
Following

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115

Jake Freimer (@[email protected]) @JakeFreimer

3 years ago

I’m hiring a computational scientist 3 at Genentech to analyze cutting-edge single-cell genomics and high-throughput screening data in an extremely collaborative environment focused on finding cures for disease. Please reach out to learn more. careers.gene.com/us/en/job/GENE…

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Hakhamanesh Mostafavi @Hakha_Most

3 years ago

We've known for a long time that a large fraction of noncoding GWAS hits are not currently explained by eQTLs. Why?? I'm excited to share our new preprint on this! Take home: GWAS and eQTL assays maximize power for different types of variants. (1/n) biorxiv.org/content/10.110…

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Sagar Bapat @bapat_lab

4 years ago

Thrilled to share findings published today @Nature from our lab in collaboration with @MarsonLab @GladstoneInst and two labs (Ye Zheng and Ron Evans) @salkinstitute. nature.com/articles/s4158…

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Zach Steinhart @CrisprEh

4 years ago

Thrilled to have our recent work from the @marsonlab published in @ScienceMagazine science.org/doi/10.1126/sc…. This was the result of an awesome collaboration between myself and fellow Marson Lab postdoc, @R_Schmidt_ (1/12)

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Stacie Dodgson, PhD @StacieDodgson

4 years ago

The @MarsonLab has a position open for a research associate to work on gene regulatory network mapping in human immune cells. Check out this related preprint: biorxiv.org/content/10.110… & apply here: bit.ly/3ohe4rM

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William J. Greenleaf @WJGreenleaf

4 years ago

Excited to announce that our paper describing NEAT-seq, a method to simultaneously measure transcription factor protein abundance, ATAC-seq, and RNA-seq in single cells, is out on biorxiv! Congrats to Amy and Ben! biorxiv.org/content/10.110…

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Daniel Bryan Goodman @dbgoodman

4 years ago

Excited to share new work w/ co-lead @CamilliaAzimi, @MarsonLab @kickassscience1 @roybal_lab: using a method we call 'CAR Pooling', we tested many CARs in multiplex & found new non-T cell signaling domains which improve CAR-T efficacy. biorxiv.org/cgi/content/sh… 👇🧵 1/10

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Zach Steinhart @CrisprEh

4 years ago

Excited to share our recent preprint from the @marsonlab, where we used complementary genome-wide CRISPRa and CRISPRi screens to map regulators of cytokine response in primary human T cells. Terrific collaboration with fellow Marson Lab postdoc, Ralf Schmidt @R_Schmidt_! (1/15)

bioRxiv @biorxivpreprint

4 years ago

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Jonathan Pritchard @jkpritch

4 years ago

How can we systematically measure gene regulatory networks around key disease genes? Excited to share our new work using CRISPR KOs in primary T cells, with @MarsonLab, led by @JakeFreimer and Oren Shaked: biorxiv.org/content/10.110…

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Sri Kosuri @srikosuri

5 years ago

Big new serology study from @MarsonLab @pdhsu et al. Lots of really detailed data on 12 different tests (10 lateral flow, 2 ELISAs). A lot of disagreement and specificity issues. Super detailed and important work. covidtestingproject.org/index.html

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Jimmie Ye @yimmieg

5 years ago

Really amazing work co-lead by my student @cody_mowery, the @MarsonLab and @pdhsu to show the performance of serological assays (lateral flow and ELISA) for detecting Sars2-CoV-2 antibodies: covidtestingproject.org.

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Jonathan Pritchard @jkpritch

6 years ago

Our latest: "GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background": biorxiv.org/content/10.110… We use urate, IGF-1, and testosterone as model molecular traits to learn general principles about the architecture of complex traits.

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Joe Hiatt @Hiattsmejoe

6 years ago

n=1 prelim optimization of CRISPR editing in lung cell lines, >80-95% efficient. An effort from @MarsonLab facilitated by @KroganLab @TheOttLab Greene lab. Hopefully this will accelerate your #coronavirus studies, share widely. We're wrestling with Calu3, plz share culture tips!

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Sri Kosuri @srikosuri

6 years ago

Unveiling SwabSeq. We repurposed a part of @OctantBio's platform to detect #SARSCoV2. We think the method is cheap (~1$), sensitive (1-6 molecules), quantitative (3-4 logs), and scalable (10k/day w/o automation; much more with). Lots of details below, I’ll lead with data [1/14]

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Jonathan Pritchard @jkpritch

6 years ago

Delighted to share our latest work, on ancient DNA of individuals from in and around Rome, spanning the last 12,000 years. At its peak Rome was the largest city of the ancient world with 1M inhabitants, controlling an empire of 70M people science.sciencemag.org/content/366/64…

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Jake Freimer (@[email protected]) @JakeFreimer

6 years ago

I'm hiring a tech to help with an exciting project mapping gene regulatory networks in primary human immune cells. Great experience with CRISPR screening, next generation sequencing, and immune cell culture. Please pass along or contact me for more info. sjobs.brassring.com/TGnewUI/Search…

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Arjun Raj @arjunrajlab

7 years ago

Okay, here's how you do the QR code for feedback: 1. Make a Google Form for your talk feedback. Here's mine: docs.google.com/forms/d/e/1FAI… What I do is make a pre-filled link (gear top right) where you pre-fill the particulars of that talk. Then…

Meilin Fernandez 🧠👩‍🔬 @MeilinFer

7 years ago

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David A Knowles (@davidaknowles.bsky.social) @david_a_knowles

7 years ago

ML, functional genomics, RNA-splicing regulation or hi-throughput screens float your ⛵️? I have postdoc positions available in my shiny new lab at @nygenome / @Columbia. Lets chat at #ASHG18 or go to nygenome.org/careers/job-po… Please RT!