Mitchell O. Roth @MitchellORoth
FSU Molecular Biophysics @mobfsu Ph.D. Candidate - Protein engineering CRISPR-Cas9 https://t.co/iAweeFxm3T… Joined July 2020-
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God, Thank you for another day. Make the most of your opportunity today. Tomorrow’s not promised.
Excited to share with you our manuscript describing the endogenous protein La as a mediator of prime editing and the development of our PE7 editor, which can improve prime editing. For more, please check out nature.com/articles/s4158…
It cannot be done, they said.. It's too flexible, they said.. 😁 biorxiv.org/content/10.110… #NPC #teamtomo #integrativemodeling by @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech et al. Great collaboration w/ Qiang Guo, Brian Chait, Javi Fernandez-Mtnz, @RoutLab_RU @salilab_ucsf
Delighted to share my solo venture, reviewing structural and mechanistic basis of RNA-based and RNA-free forms of RNase P towards substrate pre-tRNA recognition, encompassing 50 years of research, published in WIREs RNA. doi.org/10.1002/wrna.1… #RNaseP #PRORP #HARP #tRNA
science.org/doi/10.1126/sc… We look forward to working with our scientific colleagues to optimize and expand the application potential and scenarios of HYER, a new nucleic acid manipulation platform. RNA is amazing!
More exciting news - our type III-B CRISPR protease signalling story is published! Congrats to my co-first authors Jurre and @crp_salazar, the rest of the team led by Raymond Staals science.org/doi/10.1126/sc…
More exciting news - our type III-B CRISPR protease signalling story is published! Congrats to my co-first authors Jurre and @crp_salazar, the rest of the team led by Raymond Staals science.org/doi/10.1126/sc…
Want to work at the cutting edge of biomedical innovation? Join the Abudayyeh-Gootenberg Lab as a lab manager! A chance to be part of a team creating molecular technologies and AI for gene editing, RNA therapies, aging, and rejuvenation. Apply here: bit.ly/3tIIA33
I'm very excited to announce that I'll be starting my lab at @ISTAustria near Vienna this summer! The Bravo lab will be using enzyme kinetics and cryo-EM to study bacterial immunity. Read more here: bravo-lab.org
Excited to share my first work in the @MarraffiniLab, now online @Nature ! We show that type III CRISPR utilizes a transmembrane effector, which we call Cam1, to provide anti-phage immunity! Synopsis 🧵: nature.com/articles/s4158…
Our second special issue of 2023 was "Ten Years of Anti-CRISPR Research" guest edited by @joeBondyDenomy, @ARDavidson_UofT, and @theMaxwellLab. Check out the full issue here: bit.ly/3maN12H
New preprint from the lab co-led by @AmyReginaEggers and @kaichen_1990! iGeoCas9’s improved ability to rapidly unwind DNA is driven by 3 mutations. These mutations can be engineered into other Cas9’s to boost gene editing abilities! Check out @AmyReginaEggers post for details!
New preprint from the lab co-led by @AmyReginaEggers and @kaichen_1990! iGeoCas9’s improved ability to rapidly unwind DNA is driven by 3 mutations. These mutations can be engineered into other Cas9’s to boost gene editing abilities! Check out @AmyReginaEggers post for details!
I'm excited to share our findings on a metal-dependent specificity switch for #CRISPR-Cas12a! We profiled the specificity of Cas12a at four Mg2+ concentrations and observed striking differences in mismatch tolerance at lower, physiological conditions 1/n biorxiv.org/content/10.110…
Happy to share our latest story revealing how type III CRISPR-Cas ancillary effectors tactically inhibit translation to combat phage infections: science.org/doi/10.1126/sc…. Here is a thread covering major points: (1/9)
Our latest work exploring ultra rare CRISPR systems with new big data algorithms has been published by @ScienceMagazine! @zhangf @soumya_kannan12. This thread will unwrap how we found needles in a haystack of metagenomes. Let's dive in! (1/8) doi.org/10.1126/scienc…
Nothing else to say other than thank you @jordantrav13 We appreciate everything you’ve done for us JT and we pray for a speedy recovery
In a major milestone for science, for medicine, and for patients, the world’s first CRISPR drug has been approved in the UK. “A new treatment for sickle-cell disease and transfusion-dependent β-thalassemia has been authorised by the Medicines and Healthcare products Regulatory…
Researchers capture high-resolution images of #magnesiumIons interacting with #CRISPR gene-editing enzyme @NatureCatalysis doi.org/gs3f49 phys.org/news/2023-11-c…
#FSUResearch published by @NatureCatalysis: @ChemistryFsu @FSUartssciences researchers produced the first high-resolution, time-lapsed images showing magnesium ions interacting with the CRISPR-Cas9 enzyme while it cut strands of DNA. Read more here: news.fsu.edu/news/science-t…
This new paper shows the use of anti-CRISPR proteins for base editing ✏️ applications using thermostable 🔥 Cas nucleases ✂️. doi.org/10.1038/s42003…
วิหารวร.. @64nP3a15kXmk8v
69 Followers 1K Following เป็นเกียรติอย่างยิ่งที่ได้พบคุณที่นี่ หากชอบ ติดตามได้ ผมจะอัพเดตข้อมูลติดต่อในหน้าแรกได้ตลอดเวลาครับ
$ilva✝️ @silveramadi515
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Renee Hoffman @ReneeH2804
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Shelley Roth @Shelley58489043
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María (Maria del Mar.. @MariadelMarTom
11K Followers 7K Following MD Microbiologist(CHUAC-SERGAS)PhD-PI Researcher (INIBIC-SERGAS);#microbiology #phages #tolerantcells #AMR #persistercells #microTM #inibic #chuac 👩🔬🧫🦠🧬
Giulia Palermo @palermo_lab
3K Followers 2K Following Giulia Palermo Lab at the University of California, Riverside. Biophysicist passionate about Science & Art! https://t.co/FaWj1U0FtL
Christian F. Baca @ChristianF_Baca
179 Followers 228 Following PhD Candidate in the @MarraffiniLab at @RockefellerUniv and @TPCB_NYC. @UCirvine alumnus
Christian Gallardo @MrGalloLA
652 Followers 2K Following #LongRead #Sequencing of #RNAviruses and their hosts | #Genomics Tech Dev | @ScrippsResearch 🎓 | Staff Scientist @SeattleChildren | @[email protected]
Grace Hibshman @GraceHibshman
66 Followers 102 Following PhD Candidate in the Taylor Lab @ut_mbs 🔬 Capturing molecular snapshots to understand dynamics
Sarah Camara @SarahCamara94
506 Followers 425 Following PhD, excited about bacteria and their MGEs 🧬🦠
CRISPR Articles @CRISPR_JC
35 Followers 45 Following Daily updates on CRISPR technologies and applications.
Krittika Roy @KrittikaRoy28
23 Followers 88 Following Graduate Research Assistant at Institute of Molecular Biophysics, Florida State University
Michael Terns @mpterns
634 Followers 643 Following Regent’s Research Professor at The University of Georgia investigating CRISPR biology and applications
Chunyi Hu Lab @Chunyi_Hu1
248 Followers 1K Following CRISPR, Genome editing, CryoEM and explore unknown; /Assistant professor @NUSingapore; PostDoc@Cornell MBG @AilongK; Ph.D@SIBCB Yong Chen lab @UCAS1978;
AnuskaDas @AnuskaD96418956
9 Followers 42 Following
Fanxiu Zhu @FanxiuZhu
350 Followers 674 Following Virology professor, student of viruses, Marathon runner. Zhu lab studies Kaposi sarcoma-associated herpesvirus (KSHV).
Ashwanth C. Francis @AshwanthFrancis
351 Followers 453 Following Assistant Professor of Biological Sciences. understanding cell biology and evolution from the perspective of viruses
Tess McBride @Tess_M_McBride
151 Followers 156 Following Postdoctoral fellow at the Hawkesbury Institute for the Environment. Studying small secreted proteins and their role in fungal colonisation 🍄 She/her.
Debra Ann Fadool @dfadool
445 Followers 424 Following Florida State University neuroscientist, #olfactory biologist, ion channel #electrophysiology, director of postdocs, #succulent hobbyist, scout leader, #running
Louis Kolling @LJKolling
63 Followers 67 Following Postdoctoral scientist, Marcinkiewcz lab- UIowa dept of Neuroscience and Pharmacology. Biophysicist, hoister of iron, petter of dogs.
Alena Bishop @bishop_alena
176 Followers 348 Following PhD Candidate at @UCBerkeley @berkeleyMCB 🐻 Ünal and Brar Lab 🧬 | @NSF Graduate Research Fellow | @UCSanDiego grad 🌊
Kenny Collette @mrkennycollette
5 Followers 64 Following Traditional barber, musician, Doctor strange Fanatic. Deep thinker.
T. K. Märtìn Tsuï @XyzphineR
101 Followers 232 Following Ex-@Amazon structural biochemist•Activist|CRISPR⭕Virus⭕Central dogma⭕|1stGen2🏫 Pre-Twitch competitive🎮💰 Full-stack wet lab dev🧪🔬 I speak for myself
Isabel Weisheit @IsabelWeisheit
85 Followers 165 Following CRISPR and gene therapy enthusiast. PostDoc researcher @AstraZeneca, Sweden. Former PhD student @PaquetLab, Germany.
Martin Pacesa @MartinPacesa
3K Followers 931 Following Structural biologist working on 🖥️ protein design and #CRISPR-Cas systems ✂️🧬 Avid weirdness connoisseur 🎩
Phillip Kyriakakis @breakliquid
7K Followers 6K Following Senior Research Scientist at Stanford Bioengineering | Taking apart and building biology.
George Inglis, PhD @gsinglis
411 Followers 413 Following Senior Editor in the @NaturePortfolio Research Cross-Journal Team, formerly @CommsBio. 🐶 dad to Darwin. Opinions are mine (or typos). 🏳️🌈
Andrew Santiago-Frang.. @SantiagoFrangos
2K Followers 1K Following Asst Prof @Penn. CRISPR Biology & Applications | Biochemist & CryoEM | #NIHMOSAIC K99/R00 + @BWFUND PDEP Fellow. View Mine.
Connor Tsuchida @connortsuchida
945 Followers 710 Following Something new | @ForbesUnder30 ‘24 | BioE PhD @doudna_lab @UCBerkeley, @UCSF, & @IGIsci ‘23 | Via @UW @Pfizer @NYUlangone @WyssInstitute
Jun-Jie Gogo Liu @GogoLiu
517 Followers 234 Following Associate Professor @Tsinghua_Uni focusing on RNA-Biology and Gene-Editing Tech Development || Joint-postdoc @doudna_lab & @Nogaleslab
plasmidsaurus @plasmidsaurus
10K Followers 10K Following Sequencing whole plasmids, amplicons, & whole bacterial genome sequencing with ultra-fast turnaround and low prices. 500+ dropboxes globally, US & UK labs
June Richards @june_richwords
1K Followers 3K Following
Irma Querques @irma_querques
927 Followers 568 Following Structural bio(techno)logist | #NewPI at @MaxPerutzLabs | Mobile DNA lover & CRISPR newbie | @UZH_en Postdoc @MartinJinek Lab - PhD @EMBL @BarabasGroup
DNA Deviants - #Synbi.. @DnaDeviants
2K Followers 5K Following #SynBio community + biweekly journal club run by PhD students 🧬 (https://t.co/vQeIueXvsj) - msg @kkajderowicz to cohost a jclub!
Stroupe Lab FSU @StroupeGroupFSU
34 Followers 18 Following The Stroupe Laboratory at FSU researches the structrual basis for bacterial sulfur metabilism using X-ray crystallography and cryo-EM.
Ananya Sengupta @AnaSengupta
27 Followers 198 Following Graduate Student in Stagg lab at the Department of Molecular Biophysics, Florida State University
zero2launch @zero2launchdev
3 Followers 69 Following 🚀 Learn How To Code from Zero 2 Launch With No Prior Experience • JavaScript • Graphic Design • Data Analysis 📲📲 Call / Text (850) 296 7799 for CS tutoring
Hemant Goswami @HemantNgoswami
9 Followers 62 Following
Ethan Vouzas @ethanvouzas
85 Followers 185 Following PhD Candidate @ the Biological Sciences department studying DNA Replication Timing. Florida State University
Homa @HomZ66
115 Followers 132 Following
Charlisa Whyms @CharlisaWhyms
9 Followers 47 Following
Liang @LiangChenFSU
15 Followers 138 Following
Hamid Rahmani @hamid13r
216 Followers 370 Following Staff Scientist at @nani_grotjahn Lab CRYO-TOMOGRAPHY ALL THINGS!
Schmidt Science Fello.. @SchmidtFellows
6K Followers 625 Following We are developing the next generation of science leaders to transcend disciplines, advance discoveries, and solve the world's most pressing problems.
Jeff Ruffolo @jeffruffolo
2K Followers 173 Following Machine Learning Scientist @ProfluentBio | Molecular Biophysics PhD @JohnsHopkins
CRISPR Medicine @CrisprMedicine
2K Followers 249 Following We write about CRISPR Medicine – the reagents, delivery methods, safety, quality control, clinical trials, standards and best practices...
Tallahassee History @TLH_History
5K Followers 54 Following Covering the Capital City in pollen since 1824.
Oliver Rackham @TheRackhamLab
1K Followers 895 Following Synthetic biologist engineering mitochondria, RNA and new gene editing systems. NHMRC Investigator and Professor @CurtinUni and the Perkins Institute.
Silvana Konermann @SKonermann
8K Followers 562 Following Cofounder @arcinstitute and Assistant Professor @Stanford. HHMI Hanna Gray Fellow. CRISPR, RNA and Alzheimer’s via @salkinstitute, Fast Grants and @MIT.
Jonathan Weissman's L.. @JswLab
9K Followers 4K Following Jonathan S. Weissman's lab at the @WhiteheadInst/@MIT. Account run by lab members.
Melissa Kane PhD 🔬 @Cornymel
1K Followers 1K Following Assistant Professor, Center for Microbial Pathogenesis, Department of Pediatrics, University of Pittsburgh School of Medicine #retroviruses
Jesse Engreitz @jengreitz
4K Followers 405 Following Assistant Professor @stanford Genetics and BASE Initiative. Mapping the regulatory code of the human genome to understand heart development and disease.
PNAS Nexus @PNASNexus
2K Followers 492 Following PNAS Nexus is the fully open access sibling journal to PNAS (@PNASNews) & official journal of the National Academy of Sciences (@theNASciences).
Britt Adamson @bsadamson
2K Followers 604 Following scientist, mom, big fan of sleeping 8 hours in a row, she/her
Jason Sheltzer @JSheltzer
17K Followers 2K Following Assistant prof at @YaleMed. Interested in aneuploidy, mitotic kinases, drug targeting, CRISPR, and promoting diversity in science. Co-founder @MelioraTx.
Laura Sepp-Lorenzino @LauraSepplore
910 Followers 354 Following CSO @Intelliatx 🇺🇸🇦🇷 #GeneEditing #CRISPR #WomenInSTEM Opinions/likes/RT mine & not endorsements.
Sek Kathiresan MD @skathire
30K Followers 989 Following CEO @VerveTx $VERV; Imagine if a one-time treatment led to permanent lowering of LDL cholesterol: that’s what we are developing to treat heart attack
Justin Eyquem @j_eyquem
1K Followers 437 Following Eyquem_Lab / Gene Editor and Synthetic Immunologist @UCSF. Investigator @GladstoneInst and @Parkerici
Joshua Modell @jwmodell
638 Followers 192 Following Assistant Professor of Molecular Biology and Genetics @ Johns Hopkins School of Medicine
Renee Hoffman @ReneeH2804
3 Followers 5 Following
R Borza @rborza_
2K Followers 901 Following PhD Candidate at @NKI_nl #StructuralBiology〡 Curious about Synthetic Biology and Protein Design 🔬〡 Bioillustration using #b3d 🧬 | 🇳🇱 🇪🇸
NIGMS @NIGMS
21K Followers 144 Following Official Twitter account of the National Institute of General Medical Sciences, part of @NIH. Privacy policy: https://t.co/g1r5QKWMw4 Engagement ≠ endorsement
National Cancer Insti.. @theNCI
223K Followers 5K Following The U.S. government’s agency for cancer research. Part of @NIH. Engagement ≠ endorsement. https://t.co/R9SpN6R3Fq
Van Andel Institute (.. @VAInstitute
5K Followers 695 Following VAI is a biomedical research, K–12 & graduate education organization. At VAI, scientists study cancer, Parkinson’s, metabolic disorders and other diseases.
Kai Chen @kaichen_1990
1K Followers 390 Following Protein engineering, gene editing, synthetic chemistry/biology. PhD (09/15-05/20) with @francesarnold, postdoc (07/20-now) @doudna_lab.
Erin Doherty @Ee_Doherty
900 Followers 988 Following Postdoc @Doudna_Lab || @UCDChem Beal lab alum RNA Chemical Biology || she/her CIRM Postdoctoral Fellow || Former NIH F31 & NIH T32
HalicLab @LabHalic
714 Followers 252 Following Dept. of Structural Biology, St. Jude Children's Research Hospital @StJudeStructBio
Christian Gallardo @MrGalloLA
652 Followers 2K Following #LongRead #Sequencing of #RNAviruses and their hosts | #Genomics Tech Dev | @ScrippsResearch 🎓 | Staff Scientist @SeattleChildren | @[email protected]
Shelley Roth @Shelley58489043
3 Followers 77 Following
Irmantas Mogila @irmantas_mogila
95 Followers 257 Following Research assistant at Life Sciences Center @VU_LT. Studying CRISPR-Cas.
Vishnu Dileep @vishnudileep200
208 Followers 213 Following Postdoctoral fellow (NIH K99/R00) at MIT studying the genomic and epigenomic mechanisms in brain function and dysfunction.
Han Altae-Tran @altaetran
661 Followers 78 Following Fascinated by all things science. Protein designer (aka postdoc) at UW | PhD BE, MIT | MS EE, BS Math, Physics, Stanford
Dr. Danwei Huangfu @DanweiHuangfu
1K Followers 590 Following Stem cell and developmental biologist @sloan_kettering. Check out our new (in progress) website cataloging null allele phenotypes https://t.co/18ANe4FL7M
María (Maria del Mar.. @MariadelMarTom
11K Followers 7K Following MD Microbiologist(CHUAC-SERGAS)PhD-PI Researcher (INIBIC-SERGAS);#microbiology #phages #tolerantcells #AMR #persistercells #microTM #inibic #chuac 👩🔬🧫🦠🧬
FSU Research @FSUResearch
4K Followers 1K Following Florida State Office of Research telling you all about breakthroughs and discoveries @floridastate.
Giulia Palermo @palermo_lab
3K Followers 2K Following Giulia Palermo Lab at the University of California, Riverside. Biophysicist passionate about Science & Art! https://t.co/FaWj1U0FtL
Christian F. Baca @ChristianF_Baca
179 Followers 228 Following PhD Candidate in the @MarraffiniLab at @RockefellerUniv and @TPCB_NYC. @UCirvine alumnus
Russell Walton @russelltwalton
326 Followers 210 Following Graduate Student at MIT Biological Engineering and Broad Institute
Yin Lab @Yin_Lab_FSU
95 Followers 115 Following Structural immunologist @floridastate @FSUbio @FSUcmb, interested in the membranes as the intersection of inflammation and cellular homeostasis
Sarah Camara @SarahCamara94
506 Followers 425 Following PhD, excited about bacteria and their MGEs 🧬🦠
Grace Hibshman @GraceHibshman
66 Followers 102 Following PhD Candidate in the Taylor Lab @ut_mbs 🔬 Capturing molecular snapshots to understand dynamics
Randall Platt @randall_platt
3K Followers 394 Following Associate Professor @ETH_BSSE | CRISPR molecular technology development | @UUtah - @ImperialCollege - @MIT - @BroadInstitute - @ETH_en
Winston Yan @winstonxyan
1K Followers 493 Following Co-Founder https://t.co/u1aLTCtL4J, President https://t.co/kBAKlo33sB, #CRISPR wrangler. MD @HarvardMed, PhD w/ @zhangf @MIT, physics @Harvard. Enjoys Type II fun.
Nature Catalysis @NatureCatalysis
14K Followers 328 Following Nature Catalysis publishes high quality work across all areas of catalysis, including both fundamental and applied studies.
Krittika Roy @KrittikaRoy28
23 Followers 88 Following Graduate Research Assistant at Institute of Molecular Biophysics, Florida State University
Protein Data Bank @PDBeurope
22K Followers 872 Following PDBe is a founding member of the wwPDB. The PDBe team is also responsible for the PDBe-KB, AlphaFold DB and 3D Beacons resources.
The EMBO Journal @embojournal
30K Followers 645 Following Rapid publication of research in molecular, cell & organismal biology. Part of @EMBOPress. Tweets by editors. On Mastodon: @[email protected]
NatureStructMolBiol @NatureSMB
10K Followers 371 Following Nature Structural & Molecular Biology publishes top-quality research providing insight into how molecular components work together in biological processes.
Cellular repair of DNA breaks enables editing of the human genome. Do human cells repair RNA breaks, and can we use it to edit transcriptomes? Our work with @ANemudraia and @WiedenheftLab is now online in @ScienceMagazine! #ScienceResearch science.org/doi/10.1126/sc…
Congratulations to @mobfsu student Marty Campagno who studies in the @dfadool laboratory for her reappointment on the @NIH funded Chemosensory Training Grant. opda.fsu.edu/fellowships-an…
Students from @mobfsu, @FSUcmb, and @ChemistryFsu joined faculty and alumni to celebrate Michael Kasha's vision for interdisciplinary biophysical research @FSUartssciences @fsugradschool. Liang Chen, Yu Zhao, and Nidhi Walia were recognized for their recent publications.
Delighted to share my solo venture, reviewing structural and mechanistic basis of RNA-based and RNA-free forms of RNase P towards substrate pre-tRNA recognition, encompassing 50 years of research, published in WIREs RNA. doi.org/10.1002/wrna.1… #RNaseP #PRORP #HARP #tRNA
science.org/doi/10.1126/sc… We look forward to working with our scientific colleagues to optimize and expand the application potential and scenarios of HYER, a new nucleic acid manipulation platform. RNA is amazing!
Happy to be recognized by @DukeObge as one of the top instructors at @DukeMedSchool. Thank you my students - You are the best @Duke_CMB @DukeCellBiology
Excited to share my first work in the @MarraffiniLab, now online @Nature ! We show that type III CRISPR utilizes a transmembrane effector, which we call Cam1, to provide anti-phage immunity! Synopsis 🧵: nature.com/articles/s4158…
The Santiago-Frangos lab is open and ready to do some exciting research on CRISPR biology and CRISPR applications! Ecstatic to be on UPenn's campus amongst such a supportive group of excellent scientists!🤓
We are amazed and impressed that 388 scientific papers were published in 2023 after using Plasmidsaurus plasmid sequencing. We love helping you to move your research forward!
@jordantrav13 One of the best seasons in FSU history. Thank you.
Our second special issue of 2023 was "Ten Years of Anti-CRISPR Research" guest edited by @joeBondyDenomy, @ARDavidson_UofT, and @theMaxwellLab. Check out the full issue here: bit.ly/3maN12H
New preprint from the lab co-led by @AmyReginaEggers and @kaichen_1990! iGeoCas9’s improved ability to rapidly unwind DNA is driven by 3 mutations. These mutations can be engineered into other Cas9’s to boost gene editing abilities! Check out @AmyReginaEggers post for details!
Today I am excited to share our preprint “Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9” from @doudna_lab, with co-authors @kaichen_1990, Kasia Soczek, @owen_t_tuck, @Ee_Doherty, @BW_Thornton, Bryant Xu, and Marena Trinidad. biorxiv.org/content/10.110… 1/7
@jordantrav13 Jordan, you're an amazing role model for so many people.
I'm excited to share our findings on a metal-dependent specificity switch for #CRISPR-Cas12a! We profiled the specificity of Cas12a at four Mg2+ concentrations and observed striking differences in mismatch tolerance at lower, physiological conditions 1/n biorxiv.org/content/10.110…
Happy to share our latest story revealing how type III CRISPR-Cas ancillary effectors tactically inhibit translation to combat phage infections: science.org/doi/10.1126/sc…. Here is a thread covering major points: (1/9)
We are late to congratulate the newly minted @mobfsu graduate, Dr. Bhattacharya, from the @Yin_Lab_FSU. Can we also take credit for Dr. Roy, also from @Yin_Lab_FSU but a graduate of @FSUcmb.
Surgery was very successful. Thank you for all the prayers and love. All part of God’s Plan.
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