Marius Pachitariu @[email protected] @marius10p
running a lab @HHMIJanelia, data (neuro) scientist, visual cortex, large-scale recordings #Kilosort, #Suite2p, #Cellpose mouseland.github.io Janelia Research Campus Joined December 2011-
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Data from 56 different species sheds light on the diversity and evolution of cerebellar folding in mammals. elifesciences.org/articles/85907…
Out yesterday from the Singh and Carpenter labs! The CPJUMP1 Resource comprises Cell Painting images and profiles of 75 million cells treated with hundreds of chemical and genetic perturbations. nature.com/articles/s4159…
The latest version of the spike-sorting algorithm #kilosort (Kilosort4) is now out. Check out its improved performance compared to previous versions, owing to the use of a graph-based clustering approach. @marius10p @computingnature @HHMIJanelia nature.com/articles/s4159…
The Kilosort4 paper is now published @naturemethods. We put a lot of work into building and properly documenting all things Kilosort (including for older versions). w/ @computingnature #kilosort paper: nature.com/articles/s4159… code: github.com/MouseLand/Kilo…
Janelia Group Leaders @marius10p & @computingnature have released Kilosort4, the newest version of the spike-sorting software that enables scientists to understand the mountains of data collected from recording the simultaneous activity of 100s of neurons. janelia.org/news/janelia-s…
There is a lot of hype right now about Transfomers. I had assumed they were a breakthrough, but some of the early work was exaggerated and in a fair fight the metrics would be closer. This preprint suggests that in a fair fight Cellpose still wins. biorxiv.org/content/10.110…
@redklavier However, we recommend our "super-generalist" cyto3 model as it has been trained on more datasets from even more imaging modalities (github.com/MouseLand/cell…)
#Cellpose remains the state-of-the-art for cellular segmentation. See our new paper, in response to Ma et al, Nat Methods 2024. Paper: biorxiv.org/content/10.110… Leaderboard results ⬇️⬇️⬇️
🔬 Calling all #bioimageanalysis pros and fans! Seeking unique #cellpose application use cases for my computer vision students. Got any fascinating examples to share? Let's play "Will it cellpose?" Excited to see your unusual submissions! 😁 Please share on!
Excited to share that our paper on sound-evoked facial movements in mice is now out in Current Biology: authors.elsevier.com/a/1im623QW8S6D… A couple of summaries for different crowds below:
This is cool.
Today we are sharing our most complex #assembloid to date: a 4-part model of the human ascending neural somatosensory pathway generated by functionally integrating stem cell-derived cerebral cortical, thalamic, spinal and sensory #organoids. Check out the @biorxivpreprint and…
Join us for another year of the Neuromatch Academy!
Happy International Women’s Day to all my fearless brilliant women and non-binary fellow scientists cracking that glass ceiling a little more every day!
I found the main bug and fixed it (see new releases). This affects versions 2.5 and 3. Thanks to the @IntlBrainLab for finding this problem. Good time to upgrade to Kilosort4 :) ? The #pytorch implementation should be immune from such issues. #kilosort github.com/MouseLand/Kilo…
I found the main bug and fixed it (see new releases). This affects versions 2.5 and 3. Thanks to the @IntlBrainLab for finding this problem. Good time to upgrade to Kilosort4 :) ? The #pytorch implementation should be immune from such issues. #kilosort github.com/MouseLand/Kilo… https://t.co/wUkZBKTHOq
Excited to launch the new @neuromatch NeuroAI course this summer! This is our first advanced course on the shared principles of intelligence in artificial and natural systems. Applications are open until March 17th (for TAs) and March 24th (for students). neuroai.science/p/unveiling-th…
Today at #Cosyne24 @kaymtye gave a historic talk on Evolving a Toxic Hierarchy into a Sustainable Ecosystem We applaud her & you for your bravery 👏 the DEIA Committee @lukesjulson H.O. @denisejcai S.M. F.A. M.L. for spearheading & the lunch afterwards to discuss paths forward!
Kilosort4 is now fully released in #python and we have a new logo! github.com/MouseLand/Kilo… w/ Shashwat Sridhar, Jacob Pennington and @computingnature. #kilosort
Check out our lab’s recent work on visual learning and representations at the #cosyne24 #cosyne2024 workshops:
Check out our lab’s recent work on visual learning and representations at the #cosyne24 #cosyne2024 workshops: https://t.co/4FE8p5CpT3
Add these workshop sessions to your agenda to see recent work from the Pachitariu-Stringer lab at #cosyne24: whova.com/portal/webapp/… whova.com/portal/webapp/… whova.com/portal/webapp/… Work by @NunezKant , @Lin_Zhong_ion , @FarahDu6 and @computingnature.
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@marius10p @naturemethods @computingnature Congratulations guys! Such a wonderful tool… and it's really great to have a resource with all the changes (and even "lesion experiments")
@marius10p @naturemethods @computingnature Thanks Marius to you and your team for your continued work on this resource. I assume that KS4 was optimized for neuropixels, but was any testing done on v-probe data? We've had success with KS2.5 for v-probes, but would gladly upgrade if KS4 were better. Thanks again!
Out yesterday from the Singh and Carpenter labs! The CPJUMP1 Resource comprises Cell Painting images and profiles of 75 million cells treated with hundreds of chemical and genetic perturbations. nature.com/articles/s4159…
@marius10p @naturemethods @computingnature Congrats, Marius! We've been using KS4 quite a bit recently and it's great. Thank you for implementing in python and for fielding our inquiries!
The latest version of the spike-sorting algorithm #kilosort (Kilosort4) is now out. Check out its improved performance compared to previous versions, owing to the use of a graph-based clustering approach. @marius10p @computingnature @HHMIJanelia nature.com/articles/s4159…
@marius10p @naturemethods @computingnature I stopped at your poster at SFN 2023. Can TDT or plexon data be imported into this software?
@computingnature @mlphillips17 A precise, detailed, and dispassionate response. Considering the extent to which cellpose was mishandled to produce a favorable comparison in the Nat Methods paper, the tone and professionalism of this response is something to aspire to.
Transformers are not always all you need...
#Cellpose remains the state-of-the-art for cellular segmentation. See our new paper, in response to Ma et al, Nat Methods 2024. Paper: biorxiv.org/content/10.110… Leaderboard results ⬇️⬇️⬇️
@marius10p @naturemethods @computingnature Congrats! Looking forward to trying it soon!
Janelia Group Leaders @marius10p & @computingnature have released Kilosort4, the newest version of the spike-sorting software that enables scientists to understand the mountains of data collected from recording the simultaneous activity of 100s of neurons. janelia.org/news/janelia-s…
There is a lot of hype right now about Transfomers. I had assumed they were a breakthrough, but some of the early work was exaggerated and in a fair fight the metrics would be closer. This preprint suggests that in a fair fight Cellpose still wins. biorxiv.org/content/10.110…
@redklavier However, we recommend our "super-generalist" cyto3 model as it has been trained on more datasets from even more imaging modalities (github.com/MouseLand/cell…)
#Cellpose remains the state-of-the-art for cellular segmentation. See our new paper, in response to Ma et al, Nat Methods 2024. Paper: biorxiv.org/content/10.110… Leaderboard results ⬇️⬇️⬇️
🔬 Calling all #bioimageanalysis pros and fans! Seeking unique #cellpose application use cases for my computer vision students. Got any fascinating examples to share? Let's play "Will it cellpose?" Excited to see your unusual submissions! 😁 Please share on!
Excited to share that our paper on sound-evoked facial movements in mice is now out in Current Biology: authors.elsevier.com/a/1im623QW8S6D… A couple of summaries for different crowds below:
Today we are sharing our most complex #assembloid to date: a 4-part model of the human ascending neural somatosensory pathway generated by functionally integrating stem cell-derived cerebral cortical, thalamic, spinal and sensory #organoids. Check out the @biorxivpreprint and…
Happy International Women’s Day to all my fearless brilliant women and non-binary fellow scientists cracking that glass ceiling a little more every day!
Excited to launch the new @neuromatch NeuroAI course this summer! This is our first advanced course on the shared principles of intelligence in artificial and natural systems. Applications are open until March 17th (for TAs) and March 24th (for students). neuroai.science/p/unveiling-th…
Very excited to👂about Unsupervised Pretraining in Biological Neural Networks🤓 @marius10p @computingnature @Lin_Zhong_ion At the Geometry & Dynamics of Learning Workshop - A.Gajic @arna_ghosh A.Chadwick @ermgrant @helena_liu24 @smusslick @art_pel_ @rmnpogodin @stefesseM 👀