Maxime Rousseaux @maximewc
Assistant Professor and CRC studying protein mislocalization, neurodegeneration and functional genomics @uOttawaBMRI @OISB_ISBO. Co-director @GEMb_uOttawa rousseauxlab.com Ottawa, Ontario Joined February 2017-
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Great collaborating with the Russell lab on this paper. Tireless efforts from first author, Truc (Cloe) Losier, particularly in optimizing ideal screening conditions - protocol paper incoming! Nice work @OISB_IBSO @uOttawaMed
Great collaborating with the Russell lab on this paper. Tireless efforts from first author, Truc (Cloe) Losier, particularly in optimizing ideal screening conditions - protocol paper incoming! Nice work @OISB_IBSO @uOttawaMed
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Maxime Rousseaux retweeted
SUMO to the rescue! Three new studies show that tagging TDP-43 with SUMO2/3 keeps it soluble under stress, preventing the toxic aggregates that mark ALS and FTD. @uOttawa, @UNIMORE_univ, @goetheuni ow.ly/ROwi50VQk61
Maxime Rousseaux retweeted
'A stress-dependent #TDP43 SUMOylation program preserves neuronal function' Terry R. Suk @TerryRSuk Caroline E. Part, Jenny L. Zhang, Trina T. Nguyen...Maxime W. C. Rousseaux @maximewc @uOttawaBMRI @uOttawa #ALS …arneurodegeneration.biomedcentral.com/articles/10.11…
Thrilled to see our work published in its final form @MolNeuro . Outstanding work by @TerryRSuk and colleagues. Please check-out the tweetorial below. As always, happy to share reagents (plasmids are being put on @Addgene), mice and other data; just reach out!
Thrilled to see our work published in its final form @MolNeuro . Outstanding work by @TerryRSuk and colleagues. Please check-out the tweetorial below. As always, happy to share reagents (plasmids are being put on @Addgene), mice and other data; just reach out!
Maxime Rousseaux retweeted
Where are we for disease modifying therapies and Parkinson's? Why not take some lessons from multiple sclerosis? Fantastic paper by Lorraine Kalia and colleagues in @Nature Reviews Neurology. Can you say MRI? Key Points: - Guess what? ~18 disease-modifying therapies or DMTs for…
Maxime Rousseaux retweeted
I am once again posting our open 3-5 years postdoctoral position on proteostasis and aging, emphasizing that we are in beautiful, human rights-friendly and politically-stable New Brunswick, Canada. Bernie would be a regular guy here. Come join our team! postdocjobs.com/posting/728638…
Maxime Rousseaux retweeted
Cold-emailing potential postdoc advisors is a hugely successful strategy! Here is the exact e-mail I sent back in the day (& it worked) - feel free to use as a template: docs.google.com/document/d/1Ob…
Maxime Rousseaux retweeted
There is much we can learn from each other. Read the ideas on DMT discovery that came from @UofTNeurology bringing experts in #Parkinsons and #multiplesclerosis together in #Toronto (published with @SpringerNature in @NatRevNeurol) rdcu.be/dWf2U
Maxime Rousseaux retweeted
We are so proud of our team, who worked relentlessly on this project. Read about Using AI to improve the diagnosis of rare genetic disorders here: bcm.edu/news/using-ai-…
Maxime Rousseaux retweeted
How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…
Maxime Rousseaux retweeted
A new Parkinson’s gene has been discovered, RAB32. This gene is possibly involved in the same pathway as LRRK2. Great discovery by Matt Farrer and his team (who initially discovered this gene as a candidate back in 2017). sciencedirect.com/science/articl…
New paper from the lab: Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy. Congratulations to to all of those involved and thanks to @ASAP_Research and @CIHR_IRSC for the support. @uOttawaBMRI @uOttawaMed nature.com/articles/s4141…
Maxime Rousseaux retweeted
We are excited to share this comparative dataset of selective and bulk #autophagy regulators. Thanks to @maximewc for the collaboration, which created a new research focus in the lab. Comments or questions welcome.
We are excited to share this comparative dataset of selective and bulk #autophagy regulators. Thanks to @maximewc for the collaboration, which created a new research focus in the lab. Comments or questions welcome.
Happy to share the latest from the lab. A fun collaboration with @Russell_BioLab looking at stress-specific regulators of #autophagy using tandem pooled kinome screens. Feedback most welcome. biorxiv.org/content/10.110…
Maxime Rousseaux retweeted
Research Associate/Postdoctoral Fellow in Rousseaux lab at uOttawa @maximewc We are actively recruiting a Postdoctoral Fellow/Research Associate to study mechanisms underlying ALS and FTD. jobrxiv.org/job/university… #als #animal_behavior #biochemistry #... jobrxiv.org/job/university…
Maxime Rousseaux retweeted
Unpopular opinion coming up. I screen a bunch of preprints for BioRxiv, have done for a decade. I think these are fairly representative of what is published generally - e.g. similar in quality, etc., even though only ~20% of papers are preprinted. /1
New paper from the lab from the talented @HaleyMGeertsma detailing aSyn topography in the mouse brain. Implications for #Parkinsonsdisease. Thanks to @ASAP_Research for the support and to @MXHend for the fun collaboration. See below for tweetorial
New paper from the lab from the talented @HaleyMGeertsma detailing aSyn topography in the mouse brain. Implications for #Parkinsonsdisease. Thanks to @ASAP_Research for the support and to @MXHend for the fun collaboration. See below for tweetorial
🧠🚨Our lab is hiring! Please spread the word. Multiple exciting projects in the lab including a fully funded postdoctoral fellowship/research associate position. @uOttawa @uOttawaBMRI @ALSCanada @CAN_ACN
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