mathew lazarus @mlazaru
dad, trader, investor Joined May 2009-
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Herd win the North 1 group 1 sectional title. On to the group semi next Friday.
Go Herd!! Go @mlazaru!
No. 1 Mountain Lakes boys lacrosse goes south for TOC, tops No. 2 St. Augustine (PHOTOS) nj.com/highschoolspor…
Kareem Abdul-Jabbar on Aaron Rodgers: “His utter lack of even the most basic knowledge and logic is shocking.” kareem.substack.com/p/aaron-rodger…
$ONCT One of the best risk reward in small cap biotechs with so many catalysts that could move the stock this quarter. Look at the Abstract released earlier this week. This could easily double from here. 6 catalysts coming
$ONCS- $4.44/share, $165MM Market Cap: China Grand Pharma 27% holder Avidity Partners 11% holder IL-12 "turns cold tumors hot" Drug/Device combo stimulating injected DNA plasmid (IL-12) to make Keytruda more effective. Has shown monotherapy efficacy
I’m just a guy. Standing in front of the world. Asking it to care about my terminal disease. Say it with me if you would: Not today ALS. Not fucking today.
$CMPS “The magnitude of the effect we saw was about four times larger than what clinical trials have shown for traditional antidepressants on the market,” hopkinsmedicine.org/news/newsroom/…
Boy, Man, God, Shit, Camera, TV.
Agree with this. $GILD takeout of $ABUS would get them a needed siRNA HBV asset and a (very likely) piece of $MRNA.
Did a call w $GOSS IR & they commented the most exciting asset in their pipeline was GB004, $ARPO licensed asset. 004 deal was restructured, giving $ARPO $15M upfront, but decreasing milestones to $90M & mid-single royalty. $ARPO still has 20% "participation right"
$ARPO modest EV with Ph2 glaucoma data coming Q4 and COVID-19 program. Quiet on COVID front after announcing I-SPY inclusion. Could take off on any news; 9778 IND clearance, first patient in Ph2, etc.
Asymptomatic young people infected with Covid could have health consequences lasting a life time. Large numbers have ground-glass lungs on CT scan even without symptoms. Please mask if not for others, then for yourselves #MaskUp
A recent study by Blanco-Melo et al., is the first to describe the host transcriptional response to #SARS-CoV-2. The #HTGEdgeSeq Autoimmune Panel contains over 2000 genes intended to monitor immune response and response to #COVID-19 treatment. bit.ly/3084taN #HTGEdgeSeq
Pretty sure $ALT could be the real deal. I remember their story very well from when Bill was CEO. 100% efficacy in flu. Minor kinks to work out with using covid but I would think Anthrax is way harder. Low float, over a year of cash, real program. GLP aside- which is NASH future
$NK >20% move yesterday must be related to the added COVID-19 study details in their 10-Q? I don't think they had disclosed some of these details previously.
Patrick Soon-Shiong @NantKwest discusses his approach to immunotherapy, what results he’s seen to date, and why he believes what he’s learned about harnessing the immune system in the fight against cancer can be applied to treating COVID-19 soundcloud.com/levine-media-g…
mets17 @adar170
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125 Followers 4K Following Took the red pill. BTW this is purely a Matrix reference. Get your mind out of the gutter. Rick Bomstein does not exist./kev @_kevlim
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72 Followers 199 FollowingPatients Capital Mana.. @PCM_bio
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459K Followers 24K Following Covering tech, markets, AI, new energy, and autonomous electric vehicles 24/7Thanks for speaking with @skyebioscience, @adamfeuerstein ! … for the record and federal banking compliance “we are not a weed company” 😅!
My newsletter was delivered to inboxes this morning. Top item: "Weed for Weight Loss" -- a look at $SKYE and the return of CB1 inhibitors for obesity. Also, a new Bo pic! Reminder: Adam's Biotech Scorecard is free for STAT subscribers. Sign up here: statnews.com/signup/scoreca……
I turn 50 today. Rather than present some list about the 50 things I’ve learned over the past half century, I present to you the dessert that I was surprised with at dinner. Kids, stay in school….
Congratulations to Marco Dzamba and Cosmo Fusco for being recognized by NJFCA as top 100 football players for 2023. Also congrats to Darrell Fusco for being named Group 1 coach of the year. Congrats to the Herd.
Lakers wrestling wins their first state match ever over Secaucus. Second round will follow. This win breaks school record for most team wins in a season. Congratulations to the coaches and wrestlers.
@mlazaru @MaverickNY It's something we considered and patented. But the preclinical data about IL18BP blockade in our own hands was not impressive. In our tumor models, IL18BP generic deletion or inhibition only potentiated recomb WT IL18. We figured many tumors may not have much endogenous IL18.
Tonight, I want to share the incredible story that ran on @CBSSunday. The story is both a reminder of how fragile life is and a reminder of how people can do the most extraordinary things. Thank you for watching and for sharing. Good night moon. cbsnews.com/video/fighting…
Basic Math — ChatGPT vs Grok
I’m the only one working in this heat. My lawn mowers🤣🤣 already quit for the day and went into the shade…
Sure, your Hedge Fund PM’s performance may be in the top few % globally over the past five years (that’s easy stuff), but can he ALSO clear 2 acres with just a machete and a hand saw…??? Before & After
Herd win the North 1 group 1 sectional title. On to the group semi next Friday.
Two things about my daughters. First, they have endless energy and questions. Second, they make everything better. Good night moon.
Really honored to be invited to participate in this remarkable lecture series. I'm glad they didn't take my pediatric heme/onc membership card away!
Sam Blackman, MD, PhD of @DayOneBio presents his Science of Childhood Cancer Lecture on the "Opportunities and Challenges in Pediatric Oncology Drug Development: Lessons Learned from the Biopharmaceutical Industry." Join us on Oct. 12 at noon CT. bit.ly/44Wl53v @drsam
$RHHBY $RCUS $ITOS H/t @OxAnalyst If this is K-M at 2nd interim, it looks promising for the final readout on OS. Clear separation in the curves, with trend toward widening margin of benefit. HR = .81 pretty much expected Close to stat sig at .081, w/ boundary = .0336…
$RHHBY SKY-01 OS — #TIGIT $RCUS $GILD $ITOS $CGEN
Really terrific forensics here! Thanks for sharing @BioBoyScout!
For those that liked the #RNAi Clinic Timelines for $ALNY $ARWR and $NVO I posted yesterday, here's a bit more history you'll appreciate, including dropped programs. Takes blood, sweat, and tears to get this far. Charts can be found at bioboyscout.com/arwr/ under "Timeline".
Henry Winkler’s father-in-law had #AMD. Now, he wants to make sure you know about an advanced form of the disease, #GeographicAtrophy (GA). Learn more at GAwontwait.com. #WeAreApellis
$ortx achieves next funding milestone. Shows that first-class biotech investors + leading gene Tx Big Pharma still believe in future of HSC-lenti gene therapy. finance.yahoo.com/news/orchard-t… $avro
Boys Win and move to Group 1 final on Friday @4 pm at Bridgewater. Go Lakers!
Yesterday was the last game for both of my daughters’ soccer season. I made it to every game, rain or shine, because getting to see them grow up is everything.
$ARWR let that sink in - LOL!
Interesting $ARWR tidbit: since 2018 the company developed and delivered a total of 17 #RNAi drugs (3.4 per year). 3 were not advanced by $AMGN & $JNJ, 2 were dropped, and 12 currently remain in the clinic. Development and growth continues at a strong pace. Let that sink in.