Alex Perkins @TAlexPerkins
Associate Professor of Biological Sciences at Notre Dame. Mathematical modeling of infectious disease dynamics and control. Views my own. he/him/his perkinslab.weebly.com Joined September 2012-
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Great job #PerkinsLabND postdoc Abhijit Majumder sharing his expertise on within-host modeling w @NDBios @NDscience grad class on immunology. He really piqued their interests with all the possibilities these models offer in understanding within-host processes! ☘️👨🎓👨🏫🦠🤒📈📉
This article about administrative creep at universities has astonishing prescience. wapo.st/3UwsYdh
New study out! 🚨 WNV is a growing public health concern. To mitigate its effects, mechanistic models can help understand its dynamics, and predict future outbreaks. Here, we reviewed mechanistic models of WNV and delved into their aims, assumptions, and parametrization.
New study out! 🚨 WNV is a growing public health concern. To mitigate its effects, mechanistic models can help understand its dynamics, and predict future outbreaks. Here, we reviewed mechanistic models of WNV and delved into their aims, assumptions, and parametrization.
Can't help but recall the testing criteria in the earliest days of covid, when you had to be hospitalized + have an epi link to China in order to be tested.
Can't help but recall the testing criteria in the earliest days of covid, when you had to be hospitalized + have an epi link to China in order to be tested.
Thanks to @svscarpino for sharing his time & wisdom w the @lucy_institute at Notre Dame today. His talk showed what a true scholar & visionary he is. While he argued the jury is still out on predicting epidemics, he & Jesus do predict more touchdowns in ND's future. Go Irish!
Thanks to @svscarpino for sharing his time & wisdom w the @lucy_institute at Notre Dame today. His talk showed what a true scholar & visionary he is. While he argued the jury is still out on predicting epidemics, he & Jesus do predict more touchdowns in ND's future. Go Irish! https://t.co/7josg8h0pe
Data alone can’t solve our problems! This week, @svscarpino from Northeastern University will explore how the SARS-CoV-2 pandemic highlighted equity, privacy, and sovereignty issues. Learn why #GoodData is necessary and how it saves lives. RSVP here: bit.ly/4cIjYcd
Currently racing against time to make our @SunChips disappear before totality. #Eclipse2024
The Department of Biological Sciences at the University of Notre Dame seeks a broadly trained and innovative bioinformatician at the Assistant Professor of the Practice level to serve in the Genomics and Bioinformatics Core Facility. Learn more and apply: apply.interfolio.com/142498
📢 I'm Recruiting 📢 Je recrute! 🦠 Infectious disease epidemic postdoc 🏖️ Montpellier (France) ⏱️start ASAP ✅ research position inside innovative tech start-up ✅ epi modeling & risk forecasting ✅ grow impact of disease ecology in the real world 👉geomatys.com/postdoc-epidem…
Happy #PiDay to all PIs (Principal Investigators) on #NIHgrants! Treat yourself to some pie today. 🥧 We also have resources baked just for you: nexus.od.nih.gov/all/category/n…
Our new Consortium-wide paper – published today – found that catch-up immunisation activities against 14 diseases could avert 78.9% of excess deaths between 2023-2030 (95% credible interval: 40.4% - 151.4%). Abstracts also in other languages sciencedirect.com/science/articl… #vaccineswork
It's official! I'm thrilled to share that I will start a new position as Assistant Professor in the Department of Epidemiology of Microbial Diseases @YaleSPH in July 2024! For more info about the Vogels Lab check our website: vogelslab.com
Henry @kamhenrvvhas worked in collaboration with our colleagues at University of #Gondar to understand malaria importation in the highlands. Keen on doing similar work? Applications are open for our @ndeckinstitute Master in Global Health. globalhealth.nd.edu/news-events/ne…
Congrats to #PerkinsLabND @NDBios student @StacyMowry for getting a big thumbs up from her committee on her dissertation proposal! Look for exciting work from her on tick-borne disease dynamics in the years ahead.
And the next paper by @AurelHolzschuh is out: ➡️Closely related P. falciparum clones in the #Ethiopian 🇪🇹highlands ➡️Indication of onward transmission of infections imported by travelers ➡️Infections with #hrp2 deletion form closely related clusters onlinelibrary.wiley.com/doi/10.1111/me…
I am continuing to hear horror stories about the new @eLife model. The fact that the first round of reviews without any response from the authors is deemed sufficiently determinative to justify posting a public review wo consent of the authors seems wrong. And can be damaging.
The Notre Dame Mexico Global Center will host @ndeckinstitute director, Bernard Nahlen for his presentation, "The Future of Pandemics." To register to attend, visit: docs.google.com/forms/d/e/1FAI…
The Notre Dame Mexico Global Center will host @ndeckinstitute director, Bernard Nahlen for his presentation, "The Future of Pandemics." To register to attend, visit: docs.google.com/forms/d/e/1FAI…
Grab an RDT, your portable @theBentoLab and @nanopore sequencer, and get crucial #malaria parasite genomic data anywhere anytime? 🧬@AurelHolzschuh traveled to Zanzibar🇹🇿to that With @lipangalala @Fakih107 and many others @SwissTPH @NDBios @ndeckinstitute journals.plos.org/globalpubliche…
Attempting to change science center of gravity we always dreamed about this. 1st Andean school on host-pathogens dynamics was a blast. @CienBiolAndes #cienciacriolla
We're hiring! Postdoc in remote sensing and spatial ecology. See link for details and please share widely! jasonrohrlab.com/postdoc-opport…
Adam Kucharski @adamjkucharski
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42 Followers 82 FollowingSo, *preliminary* molecular clock analyses indicate that the time of the most recent common ancestor (TMRCA) of the US cattle flu clade was late December. TMRCA of that clade and the closest relatives in birds, mid-December. If single intro, likely between those rough dates.
@drseanmullen I have started emailing their professors with alternative ideas 🙃
I recently learned about the term “salami slicing tactics” in geopolitics and this explains so much about the bureaucratic creep of university policies. en.wikipedia.org/wiki/Chinese_s…
Here's a visual of the US H5N1 "Cattle clade", HA plus two internal genes. Strongly suggests to me there was single origin, at least for these sequences. Possibly in late 2023/early 2024.
⚠️ BREAKING: Mysterious outbreak,Covid-like pneumonia infects 60 people in Buenos Aires of Argentina 🇦🇷 Doctors are on high alert over a mystery flu-like illness with similarities to Covid-19 that has people critically ill in Argentina. @ejustin46 @DavidJoffe64 @LauraMiers
I've greatly expanded my chapter on Bayesian clinical trial design with examples of Bayesian power and sample size simulations for time-to-event and ordinal outcomes, incorporating uncertainty in effect size to detect ... hbiostat.org/bayes/bet/desi… @vandy_biostat
I think probably predictable. researchgate.net/profile/Franci… MPox cases Nigeria 2017-2022. Gender distribution: male>>female and …
@PeterHorby @PSIOxford That said, a lot of mpox transmission in Africa is not sexual, and genital lesions can occur in generalised mpox that occurs following non-sexual transmission. Mpox finding a foothold in GBMSM sexual networks outside Africa in 2022 was unexpected and (reasonably?) not predicted.
1/n I’m seeing on social media and popular podcasts, awful nonsense and false claims about Covid immunizations in pregnancy causing autism in newborns. This is dangerous health disinformation at multiple levels. Here is the real story.
(Tweets #4-15 = short detour on chronic infections) Nearly all major SARS-CoV-2 variants have, IMO, originated in chronic infections. And to paraphrase @SolidEvidence, chronic infections are where this virus goes to college. 4/120 x.com/solidevidence/…
We know now that people can be infected for months or even years with SARS-CoV-2 in some instances, and this is basically like sending the virus to college. 20/
What connects two regions on opposite ends of NSP12, a narrow slice of an obscure NSP3 region (DPUP/SUD-C), & a 3-AA sliver of nucleocapsid (N)? I have no idea, but I’m convinced there’s a link that could help reveal the inner workings of SARS-CoV-2. 1/120
Take a look at how the number of federal regulations and policies governing research at universities has dramatically increased over the years. This adding an enormous cost of doing research. (Source COGR)
Over and over again, I hear my Republican colleagues talk about the high cost of addressing the climate crisis. Well, maybe we should be asking them about the high cost of not addressing it at all.
New study calculates climate change’s economic bite will hit about $38 trillion a year by 2049. apne.ws/jYez35j
What is wrong with @BioRender, you ask? Besides other issues raised in this thread: x.com/baym/status/17… @baym put it clearly: imagine if Microsoft or Adobe did the same!
I also want to brag about how @nquinoneso made such incredibly good figures that the journal sent it back with concerns we’d used a professional service without citing it!
Informative article on highly pathogenic avian influnza H5N1 in dairy cows in the USA. Recommended. #vogelgriep latimes.com/environment/st…
The testing approach to H5N1 in cattle (in the link) needs to change substantially. @USDA_APHIS may be doing what it can now with minimal resources, but testing needs to expand, get simpler, more available and transparent. aphis.usda.gov/sites/default/… 1/x
Nigeria becomes first country to roll out new meningitis vaccine, @WHO says reuters.com/world/africa/n…
#dengueTracker provides weekly estimates of #dengue cases in #Brazil 🇧🇷 We added new analyses and interactivity for better surveillance🦟📈🏥 👉 diseasesurveillance.github.io/dengue-tracker… @guipsoares @rizbicki @leosbastos @Catoper @ISNTD_Press @GlobalVectorHub @ensp @fiocruz @opsoms @pahowho
@HelenBranswell Wow, that looks bad. Crucial to know asap how those cattle are getting infected. Contaminated feed (infected poultry?) vs other cows make a crucial difference in scale of concern.
@TAlexPerkins @svscarpino @lucy_institute Ah makes me miss Notre Dame.
@TAlexPerkins @lucy_institute Thanks SO much for hosting me!!!