Kiran Girdhar @Kirangirdhar
Functional Genomics of Brain. Computational Biologist. Manhattan, NY Joined December 2009-
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A 🧵 on some of my intuitions/priors about the genetics of complex and molecular traits in humans (i.e. what I think of as typical), largely motivated by GWAS/QTL studies over the past decade [citing papers with nice figures where possible]
The website for the Center for Disease #Neurogenomics is LIVE! Led by @panos_roussos, this is one of few centers in the world w access to brain tissue & population-level datasets. Learn more: icahn.mssm.edu/research/neuro… @SinaiBrain @IcahnMountSinai @IcahnInstitute @SinaiGenHealth
Thrilled to share our study in @NatureGenet on population-level analysis of transcribed enhancers. Thanks to my colleagues at @LabRoussos and reviewers for helping to improve it. nature.com/articles/s4158…
I am super excited to announce that our new review on "how a massively parallel reporter assay (MPRA) can be used to interrogate variant function" is finally out! jneurodevdisorders.biomedcentral.com/articles/10.11…
We are thrilled to share our work on microglial genetic regulatory landscapes in Alzheimer’s Disease. Check out our key findings and thanks to all involved! @SinaiBrain @SinaiGenetics @MountSinaiPsych @IcahnMountSinai #MicrogliaADgwas doi.org/10.1038/s41588…
"Who wants to coordinate the seminars next year?"
Very excited to share that I recently started at Ionis as Director in Human Genetics with a vision to establish a human genetics group that integrates into their drug discovery and development pipeline!
I am happy to announce that the lab's new paper on substance use genetics is out in Molecular Psychiatry! This was led by a talented grad student Nancy with amazing collaboration with @AkbarianLab, @DanaBHancock, and Eric Johnson. nature.com/articles/s4138…
Bioinformatician-2 position at Roussos lab. DM me if you are interested in this position. careers.mountsinai.org/jobs/2758002?l…
Delighted to share our expert review: What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding nature.com/articles/s4138…
Histone modifications linked to 3D genome organization in PFC samples from 388 neurotypical individuals and 351 individuals diagnosed with #schizophrenia or #bipolar disorder New from @Kirangirdhar @AkbarianLab @LabRoussos @g_e_hoffman @JaroslavBendl nature.com/articles/s4159…
ElmaSenior @8cV9k95Mv6kxWh4
0 Followers 167 Following
Hesay @Hesay521290
0 Followers 202 Following Life itself is a journey, we are all worthy and should strive to travel to different lives.
Solimpe @Solimpe188491
52 Followers 2K Following
Anjali Chawla @TrippyNeuron
35 Followers 42 Following PhD candidate in Neuroscience, McGill University. #HBHL #DKG #FRQS fellowship recipient. Studying #epigenetics in the human brain at single-cell resolution.
An Hoang @Bun_Without_B
168 Followers 1K Following Using data and biology to explore the beauty of life
Yuki Miura @myym_yuki
579 Followers 501 Following Research scientist @Sergiu_P_Pasca 's Lab @Stanford, studying human brain development, cortico-striatal neural circuits and disease. Tweet sciences and photos.
Erin Jimenez @ErinJimenezPhD
1K Followers 1K Following assistant professor @JohnsHopkins | hair cell regeneration | pugilist @levelupboxing | IG thejimenezlab |she/her
Sasha Gusev @SashaGusevPosts
9K Followers 3K Following Statistical geneticist. Associate Prof at @DanaFarber | @harvardmed | @DFCIPopSci
David Burstein @DavidBPhD
10 Followers 43 Following Senior Data Scientist @IcahnMountSinai, Center for Disease Neurogenomics 🧬 🧠 All views expressed are my own.
Swapnil Tichkule @TichkuleSwapnil
6 Followers 28 Following
Koyal Garg @GargKoyal
346 Followers 577 Following Associate Professor of BME | Musculoskeletal Tissue Engineering | Biomaterials | Stem Cells
Kristen R Maynard @kr_maynard
440 Followers 192 Following Neuroscientist @LieberInstitute using a cross-species approach to study cell type and circuit-specific gene expression changes in psychiatric disease.
fenna krienen @fennamk
1K Followers 572 Following Assistant Professor, Princeton Neuroscience Institute
Mount Sinai Psychiatr.. @MountSinaiPsych
3K Followers 935 Following The Department of Psychiatry at @MountSinaiNYC and @IcahnMountSinai
Dominik Szabó @domSzabo
294 Followers 1K Following Comp Biol PhD candidate @apombo1 lab @BIMSB_MDC. Thinking of human DNA as the most elaborate code. Aiming to understand its 3D dependent compilation
Neha Raghavan @nehsayer
167 Followers 554 Following Neuroscience Genetics // some thoughts from my mind, about the mind
Matt Girgenti @MattGirgenti
747 Followers 1K Following Assistant Prof @YalePsych and @DeptVetAffairs. Single-cell, Genomics, Neuroscience, Psychiatric Genetics. Dad of 2. MtG collector. Opinions are mine
Swadha Singh @swadha22
105 Followers 88 Following Neuroscientist unraveling mysteries while juggling mom life in the NYC 🧠👩👧 | from India | Striving to make a meaningful mark
Dr. Srishti Nayak �.. @dr_srishtin
2K Followers 5K Following Faculty @VanderbiltENT 🎵👂💬🧠🧬 | Interdisciplinary science of language-music-hearing @NIDCD @NIHdatascience | Taught @Princeton | PhD @BU_tweets | Views mine
Sankalp Shukla @Sankalp_Shukla_
249 Followers 1K Following PhD @Penn | Undergrad @IITKanpur | Membrane biophysics | Neurodegeneration.
Kavita Praveen @B_KavitaPraveen
138 Followers 76 Following
ACNP @ACNPorg
9K Followers 2K Following The American College of Neuropsychopharmacology (ACNP) is the nation's premier professional society in brain, behavior, and psychopharmacology research.
Daniel Pérez @DanPerez0
93 Followers 1K Following A physicist interested in active matter | genomics & mechanobiology | AI applications
Rachel EH Sager, PhD @REH_Sager_PhD
145 Followers 601 Following Post-doctoral researcher focusing on brain development, schizophrenia, and the role of the immune system therein. Pronouns she/her.
Sandip @SandipOff
27 Followers 99 Following Bioinformatics Research Scientist at Nathan Kline Institute (RFMH). Interests in NGS, Proteomics of whole Brain, Synapse.
Eilis Hannon @eilis_hannon
664 Followers 2K Following Mathematician turned Bioinformatician. EPSRC Research Software Enginerring Fellow. Wannabe domestic goddess, one science themed cake at a time.
bhavya gohil @Bhavya_Gohil_
616 Followers 5K Following Wandering & exploring science. On the quest to understand life! Research assistant @DBT_NBRC Alum @vsicmb @Themsubaroda |Dog parent|
B P Kailash @KailashBP10
300 Followers 2K Following PhD Candidate, @towfiqueRaj Lab, Icahn School of Medicine at Mount Sinai. Alumn @iitmadras.
Lachlan Gilchrist @lgilchrist1
402 Followers 1K Following @KCLDriveHealth PhD student @KingsIoPPN || Statistical Genetics, Neurodegeneration, Psychiatry, Dementia, Biomarkers
Silvia De Rubeis @DeRubeisLab
1K Followers 975 Following Neuroscientist & geneticist studying 🧠 development & autism | Immigrant | 2x mom | #firstgen | #Humboldtian | Opinions are my own (she/her)
Shreya Kashyap @snkash
384 Followers 983 Following Aspiring physician-scientist @UABMSTP; PhD from @RobersonLabUAB; lover of dance, coffee and kittens
Daniel Cohrs, MD @DanielCohrsMD
435 Followers 1K Following Resident physician in psychiatry. Interests: philosophy of psychiatry/science, safe de-prescribing, various other things.
حسين @EagleHuss
6K Followers 457 Following Investigating the human brain in relation to behavioral performance and emotional stability || #CAT #neuroergonomics اعتذر عن تقديم الاستشارات
Olicier PIERICHE @PiericheOlicier
319 Followers 988 Following Avocat, Dipl, Écrivain, Théologien, Ex- Consul General Ex Ministre des Haïtiens Vivant a l’Etranger, Pdt Parti RECONSTRUIRE HAÏTI, Notary, Founder BTKA PDG ETMS
Alexi Nott 🏳️.. @nottalexi
1K Followers 2K Following Group Leader at UK Dementia Research Institute at Imperial @ukdri | Lecturer @imperialbrains | Epigenetics in brain disorders | LGBTQ+ champion | He/him
Avner Schlessinger @SchlessingerLab
3K Followers 3K Following Computational biologist. Professor. Co-Director of Disease Mechanisms and Therapeutics Training Area @IcahnMountSinai. Opinions are mine. #DrugDesign #AI
Sarah Marzi @sj_marzi
4K Followers 2K Following Senior Lecturer and @UKDRI Group Leader @KingsIoPPN #epigenomics #neurodegeneration 🧬🧠
Jonathan DePierro PhD @jon_m_depierro
2K Followers 5K Following Assoc Professor & Assoc Director #CSRPG @MountSinaiPsych @CambridgeUP author: https://t.co/fhQT9dMmC1 EIC Psych Quarterly @springerpub Opinions are my own.
Jonelle D. Villar @jdvillar
286 Followers 1K Following Psychiatric nursing | PhD candidate @medofak_uib | DNA methylation & severe mental disorders #schizophrenia | #RLadiesBergen 👩🏻💻👩🏼💻👩🏾💻 #openscience
BrightFocus Foundatio.. @_BrightFocus
17K Followers 3K Following BrightFocus funds groundbreaking research in an urgent effort to discover cures for Alzheimer's disease, macular degeneration and glaucoma.
Carolyn Bertozzi @CarolynBertozzi
78K Followers 3K Following Prof. @StanfordUChem; Baker Family Director, @Stanford_ChEMH; @HHMINews Investigator; EIC of @ACSCentSci; She/Her 🏳️🌈
Shailaja Chandra @over2shailaja
7K Followers 477 Following Author,OPED writer,commentator on public policy.(IAS past.) RTs aren’t endorsements.Never despair!
Zehao Zhang @Tommyz626
73 Followers 152 Following Graduate fellow @junyue_cao's lab @RockefellerUniv Studying aging biology and genomics
David J. Linden @david_j_linden
3K Followers 492 Following Johns Hopkins neurobiologist and author. Latest book: "Unique: The New Science of Human Individuality" published by Basic Books.
Siddha Performance @KapilGuptaMD
105K Followers 0 Following Direct Truth. Conquering the Mind. For Life. And Elite Human Performance. Kings. Queens. CEO's. Performing Artists. Professional Athletes.
TF binding papers �.. @TF_binding_bot
4K Followers 11 Following Papers on transcription factor binding #TFbinding. Maintained by @TeifLab. Also see @nucleosome_bot, @CTCF_papers, @DNAbinding, @cfDNA_papers, @generegulation
CTCF Papers 📚 @CTCF_Papers
3K Followers 10 Following PubMed bot reporting all CTCF papers. Maintained by @TeifLab. Also see @TF_binding_bot, @Nucleosome_Bot, @generegulation
Denise J. Cai, Ph.D. @denisejcai
8K Followers 1K Following Prof. of Neuroscience @SinaiBrain · Investigating memory stability & flexibility · Advocate for open science · Mom of two littles · Amateur chef · she/her
Keri Martinowich @martinowk
3K Followers 1K Following Neuroscientist @LieberInstitute @HopkinsMedicine studying molecular regulation across species in circuits impacted in complex brain disorders. Own opinions.
Samantha Morris @morris_lab
10K Followers 874 Following Reprogramming and single cell biology. Associate Professor @WUSTLmed. Allen Distinguished Investigator. Associate Editor @Dev_journal. CEO CapyBio
Sandip @SandipOff
27 Followers 99 Following Bioinformatics Research Scientist at Nathan Kline Institute (RFMH). Interests in NGS, Proteomics of whole Brain, Synapse.
Marieke Kuijjer @mkuijjer
1K Followers 665 Following Mixed bag of computational biology and cancer research. Group leader at NCMM, University of Oslo @[email protected] @mkuijjer.bsky.social
Evan Macosko @macosko
3K Followers 362 Following Genomics technologist, Psychiatrist, Associate Professor, Massachusetts General Hospital @broadinstitute. Founder, Curio Bioscience
uri alon @UriAlonWeizmann
11K Followers 518 Following The Alon lab explores design principles of biological circuits, focusing on systems medicine, ageing and healthspan.
Pete Kraft @GENES_PK
4K Followers 376 Following Director, Transdivisional Research Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute | Views are my own.
Krithika Venkataraman.. @kritvenks
1K Followers 3K Following Scientist @SimonsFdn // alumna: Vosshall Lab PhD 🦟 + Civic Science Associate @rockedu_ + @smithcollege // she/her (views = personal) // @kritvenks.bsky.social
Nature Biotechnology @NatureBiotech
302K Followers 2K Following Publishing the very best of biotech science and business. Part of @SpringerNature and @NaturePortfolio. On Facebook (natbiotechnol) & IG (nature.biotechnology)
Doudna Lab @doudna_lab
71K Followers 88 Following News from Jennifer Doudna's lab at @UCBerkeley @igisci. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only.
Icahn School of Medic.. @IcahnMountSinai
30K Followers 1K Following An international leader in medical and scientific training, biomedical research, and patient care. It is the medical school for @MountSinaiNYC.
Christian Porras @ChrisAPorras
89 Followers 194 Following MD/PhD Candidate 🩺 🧠 @IcahnMountSinai @LabRoussos
Milos Pjanic @MilosPjanic
4 Followers 2 Following
Nowakowski_Lab @LabNowakowski
3K Followers 1K Following Developmental neurobiologist, using integrative high throughput technologies to study how the cerebral cortex is constructed.
Arnold Kriegstein @Kriegsteinlab
1K Followers 6 Following I am a neurologist and a developmental neuroscientist with a lifelong fascination with the workings of the human brain.
Yonatan Perez @Yonatan_Peretz
144 Followers 181 Following Deciphering molecular pathways of neurodevelopmental disorders using gene editing techniques, 3D stem cell models, postmortem tissue, and single cell genomics
Anjali Chawla @TrippyNeuron
35 Followers 42 Following PhD candidate in Neuroscience, McGill University. #HBHL #DKG #FRQS fellowship recipient. Studying #epigenetics in the human brain at single-cell resolution.
Yuki Miura @myym_yuki
579 Followers 501 Following Research scientist @Sergiu_P_Pasca 's Lab @Stanford, studying human brain development, cortico-striatal neural circuits and disease. Tweet sciences and photos.
An Hoang @Bun_Without_B
168 Followers 1K Following Using data and biology to explore the beauty of life
kapoorlabs @kapoorlabs
166 Followers 153 Following KapoorLabs’s mission is to ensure that artificial intelligence benefits researchers engaged in understanding and curing Cancer.
Prachee Avasthi @PracheeAC
25K Followers 8K Following Co-founder & CSO @ArcadiaScience. Head of Open Science @AsteraInstitute. Immigrant. she/her
Becca Mason | PhD | C.. @beccamasonphd
2K Followers 316 Following Associate Professor and certified coach helping assistant professors succeed on the tenure track 👩🏫
Seqera @SeqeraLabs
2K Followers 11 Following The leading provider of open source workflow orchestration software for data pipelines, cloud infrastructure & collaboration. From the creators of @nextflowio.
Shawn Burgess burgess.. @SMBurgessLab
2K Followers 329 Following zebrafish researcher, interested in hearing regeneration, opinions are mine and mine alone. he/him
Erin Jimenez @ErinJimenezPhD
1K Followers 1K Following assistant professor @JohnsHopkins | hair cell regeneration | pugilist @levelupboxing | IG thejimenezlab |she/her
Dr. Pedrelli @ppedrelli_paola
525 Followers 458 Following Psychologist and Faculty @MassGeneral and @HarvardMedicalSchool, Research on mood disorders, affective computing, heavy episodic drinking. She/Her
magdalena janecka @magdalena_u_j
320 Followers 298 Following psychiatric epidemiology @nyulangone (she/her) // IG: muj_pottery
Ron Do @DoGenetics
1K Followers 855 Following Human Geneticist. Data Scientist. Professor @IcahnMountSinai @BronfmanInst
Siegenthaler_Lab @SiegenthalerLab
13K Followers 7K Following Neuroscience, meninges, brain vasculature, blood-brain barrier, cake (or cookies)
Xiaole Shirley Liu @XShirleyLiu
9K Followers 70 Following Computational biologist specializing in data sciences of transcriptional and epigenetic gene regulation, CRISPR screens, and cancer Immunology
Feng Zhang @zhangf
50K Followers 42 Following Researcher at Broad Institute and McGovern Institute at MIT.
Daniela Witten @daniela_witten
49K Followers 754 Following dorothy gilford endowed chair and prof of stat/biostat @uw. all views my own.
Prerna Malaney @pre_RNA7
699 Followers 843 Following RNA-binding proteins| Asst. Professor @DartmouthBCB @DartmouthCancer| Postdoc @MDANews| PhD @USouthFlorida| Undergrad @ICTMumbai1933
Gabriela K. Popescu @PopStarLab
2K Followers 2K Following President of the Biophysical Society | Scientist and Professor | Mentor and Learner | ExtraVagant Grandmother
Sasha Gusev @SashaGusevPosts
9K Followers 3K Following Statistical geneticist. Associate Prof at @DanaFarber | @harvardmed | @DFCIPopSci
Nathan Reticker-Flynn @RetickerFlynn
1K Followers 671 Following Tumor Immunologist and Engineer @Stanford.
Rong Fan @RongFan8
9K Followers 1K Following Harold Hodgkinson Professor of Biomedical Engineering and Pathology, Yale University https://t.co/kLH8WPg2c2 https://t.co/kbDKoBh9Ak https://t.co/MduFkomdDj
Raphael Gottardo 📊.. @raphg
3K Followers 2K Following Director Biomedical Data Science Center and Professor @CHUVLausanne @unil. Immunology, Immunotherapy, Single-Cell, Statistics and Machine Learning.
#postdocs are engines of scientific progress. The project we are undertaking (isolating live cells from autopsy) is ambitious often having to drop nights/weekend plans. Thanks to amazing team @DanieleMattei4 @oriolnarcis @AliceBuonfi & Elena for all their hard work!! #Alzheimers…
Sorting #Microglia and #Monocytes from human PD donors in the myeloid-busy Raj lab! @oriolnarcis @AliceBuonfi @towfiqueRaj
Reposting my offer: 1-1 mentoring by phone on anything science/career related! Have talked to undergrads to tenured faculty and everything in between. Email me to find a time. As always, very happy to chat with people from diverse backgrounds.
Reposting my offer for 1-1 mentoring on, well, just about anything! Faculty and grad app season is upon us, but anything goes. Email me for a time. As always, very happy to chat with people from diverse backgrounds.
PhD student trying to leave before the revisions for his paper are finished
It’s been 10y since we opened our lab at @IcahnMountSinai. What an exciting ride and supportive environment it has been. We are now moving to @Columbia @ColumbiaPeds. Thrilled at the future and discoveries in genetics and immunology to come.
Data analysis tip: look for extremal points in every plot and don’t let go until they can be fully explained. Sometimes they are not physically possible, pointing to a bug. Sometimes they can reveal something interesting. Whatever they end up being, they *must be explained*.
Faculty application season is upon us! Offer for 1-1 mentoring stands. (Also applies to anybody from undergrads to faculty.) Email me to find a time. Especially happy to speak with people from diverse backgrounds.
3/ Getting fired, and very coldly, was a horrible feeling. I got instantly sick and stayed in my then gf’s (now wife’s ❤️) bed for 4-5 days. I had poured a lot of myself into helping build the company - it felt like a part of me got ripped out.
2/ The first 18 months were one of the best times I had in science. I learned how much I loved starting things, being part of a team working together, & what I was capable of when focused.
Jason Buenrostro (@JD_Buenrostro) is a cellular and molecular biologist and 2023 MacArthur Fellow investigating the mechanisms that regulate gene expression. #MacFellow Explore his work and all the 2023 MacArthur Fellows on our website! macfound.org/fellows/class-…
"Excited to share our latest preprint from @LabRoussos on to-date largest cell-specific ATAC-seq dataset generated from the PFC and ACC regions” medrxiv.org/content/10.110… @JaroslavBendl
The book aims to provide a unified view of human variation, population genetics, human history and trait genetics / GWAS I wrote this partly because I find a lack of suitable readings for teaching, and partly to connect the popgen and statgen world views in an accessible format
Sitting here wondering with a trainee wondering about the real opportunity cost to the trainee to waiting for reviews…
Setting aside all the moral arguments, as a practical matter, should we be paying peer reviewers some amount of money to try and get reviews on time? The review process has become really slow.
Thrilled to share that I'll be joining @harvardmed’s Dept. of Neurobiology & the @KempnerInst as a founding faculty member in September 2023: harvard.edu/kempner-instit…
A few years ago I requested access to GWAS summary statistics from a variety of published studies that stated "Data Available Upon Request" and tracked the process: 4 studies, ~40 emails, 2 provided the data, taking an average of 22 weeks. Not great!
The response I received when very kindly asking a Cambridge Prof if they would share their GWAS sumstats, also said I’d include them as coauthors on any resulting papers… I.e. no, go and run the whole GWAS again yourself. THIS IS BAD SCIENCE. Also, not even a Dear Emma? Rude.
@SashaGusevPosts Yeah, 'data available upon request' slows things down at best, and is all too often a joke. It's sad to me that people work hard on a study and then do their best to limit the value of their work.
@SashaGusevPosts Yeah it took me 8 no response emails over three months before I I heard back from a co-author that the summary statistics would be shared on their web portal. However, for another GWAS the researcher sent them to me the same day! 🤷
I often crib that we don't have enough compute & storage to accomplish some of our "big ideas". But then we often come up with other ideas that are leaner & far more efficient than the big ideas. Sometimes having just the right amount of constraints forces u to innovate. 1/
@arjunrajlab @kat_shkarina A focused project along the general aims of the lab's current funding, and a "top secret" project to develop your own idea that you are excited about.
@kat_shkarina My main tip is… try and avoid multiple projects. The overhead of switching along with various psychological challenges make it very hard. I recommend trying to offload the projects you are least excited about as fast as possible.
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