Your Protocol @your__protocol
🧠 The world's best minds, one platform. 🧬 Science-backed protocols for high performance. 📋 Every claim graded and cited. 🔎 Find Your Protocol ↓ yourprotocol.ai Miami, FL Joined May 2024-
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Holt-Lunstad et al, PLOS Medicine 2010, PMID 20668659. Evidence: moderate, large observational review.
Weak social ties may be as risky as smoking. A review of 148 studies and 308,849 people found strong relationships predicted meaningfully lower death risk than weak ones. The effect size beat obesity and inactivity as risk factors.
Marconi et al, Schizophr Bull 2016, PMID 26667445. Evidence: moderate, pooled observational data, clear dose response.
Heavy cannabis use carries one real risk: psychosis. A review of 10 studies, 66,816 people, found the heaviest users were almost 4 times more likely to develop psychosis. Occasional use showed a much smaller signal.
Leong et al, Lancet 2015, PMID 25982160. PURE study, 139,691 adults, 17 countries. Evidence: strong.
Grip strength beat blood pressure at predicting death. A study of 139,691 adults in 17 countries found weaker grip predicted earlier death better than systolic blood pressure did. Lifting weights after 40 is how you keep it.
Hultman et al, J Appl Physiol 1996, PMID 8828669; Vieth et al, Am J Clin Nutr 2001, PMID 11157326. Evidence: strong, two controlled human trials.
Creatine kicks in fast. Vitamin D3 does not. A loading dose of 20 grams a day maxes out muscle creatine in about 6 days. Vitamin D3 takes 3 months to plateau, at any dose, because of how long it stays in blood.
Peterson et al 2011, Med Sci Sports Exerc: 49 studies, 1,328 adults over 50, resistance training versus lean mass gained. Grade: strong.
Muscle mass drops 3 to 8% every decade after age 30. Combining 49 studies and 1,328 adults over 50, resistance training added back about 1.1 kg of lean mass. Walking and biking protect your heart. They do not reverse this. Lift heavy 2 to 3 times a week instead.
Chlebowski et al 2020, JAMA: Women's Health Initiative, 27,347 postmenopausal women, 20-year follow-up. Grade: moderate.
Hormone therapy and breast cancer get treated as one fact. It is actually two. A 20-year study followed 27,347 women. Estrogen alone lowered breast cancer deaths. Combined estrogen plus progestin raised cases the longer it was used. Ask your doctor which type you'd be taking.
Guasch-Ferre et al 2014, BMC Medicine: PREDIMED trial, 7,216 adults in Spain, about 5 years follow-up. Grade: strong.
Bryan Johnson drinks a lot of olive oil. That part has real backing. A trial followed over 7,000 adults in Spain for about five years. People who ate the most olive oil had a 48% lower risk of dying from heart disease. His daily pill stack has no trial support like this.
Steiner et al 2017, JAMA: 750 women aged 30-44 followed for up to a year trying to conceive naturally. Grade: moderate.
AMH is a blood test sold online to predict fertility. 750 women were tracked for a year trying to conceive. Low-AMH women conceived at nearly the same rate as normal-AMH women: 65% vs 62%. The test is built to plan fertility treatment, not to judge your chances.
Klein 2015, J Hum Nutr Diet: no RCTs of commercial detox diets in humans. Grade: UNSUPPORTED. van der Schoot 2022, AJCN: 16 RCTs, fiber response 66% vs 41% control. Grade: MODERATE.
Nobody has properly tested a commercial detox diet in people, a 2015 review found. Fiber has been tested: across 16 trials, 66% of adults with chronic constipation responded to fiber vs 41% on control. Add fiber slowly and drink water.
Hughes 2013, Ann Intern Med: Nambour RCT, daily broad-spectrum sunscreen vs discretionary use; daily group showed no detectable increase in skin aging over 4.5 years. Grade: STRONG.
Daily sunscreen slowed skin aging in a long-term trial. The daily group aged 24% less than people who used it only when they chose to. Wear sunscreen every day before you buy another anti-aging cream.
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